Stretch‐driven microfluidic chip for nucleic acid detection
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27839
Abstract: Molecular diagnosis is an essential means to detect pathogens. The portable nucleic acid detection chip has excellent prospects in places where medical resources are scarce, and it is also of research interest in the field… read more here.
Keywords: microfluidic chip; detection; chip nucleic; acid detection ... See more keywords
DNA fragment‐assisted microfluidic chip for capture and release of circulating tumor cells
Sign Up to like & getrecommendations! Published in 2019 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201900165
Abstract: Circulating tumor cells are specifically referred as cells that detached from the primary tumor and are present in the bloodstream. They could be isolated from blood and used as representative biomarker for predicting cancer prognoses.… read more here.
Keywords: microfluidic chip; tumor cells; circulating tumor; capture ... See more keywords
Rapid multi‐attribute characterization of intact bispecific antibodies by a microfluidic chip‐based integrated icIEF‐MS technology
Sign Up to like & getrecommendations! Published in 2022 at "Electrophoresis"
DOI: 10.1002/elps.202200165
Abstract: Rapid, direct identification and quantitation of protein charge variants, and assessment of critical quality attributes with high sensitivity are important drivers required to accelerate the development of biotherapeutics. We describe the use of an enhanced… read more here.
Keywords: chip based; microfluidic chip; charge variants; charge ... See more keywords
Construction of Exosome SORL1 Detection Platform Based on 3D Porous Microfluidic Chip and its Application in Early Diagnosis of Colorectal Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202207381
Abstract: Exosomes are promising new biomarkers for colorectal cancer (CRC) diagnosis, due to their rich biological fingerprints and high level of stability. However, the accurate detection of exosomes with specific surface receptors is limited to clinical… read more here.
Keywords: sorl1 detection; microfluidic chip; crc; detection ... See more keywords
A facile strategy to integrate robust porous aluminum foil into microfluidic chip for sorting particles
Sign Up to like & getrecommendations! Published in 2017 at "Microfluidics and Nanofluidics"
DOI: 10.1007/s10404-017-2001-9
Abstract: Abstract High efficiency integration of functional microdevices into microchips is crucial for broad microfluidic applications. Here, a device-insertion and pressure sealing method was proposed to integrate robust porous aluminum foil into a microchannel for microchip… read more here.
Keywords: microfluidic chip; aluminum foil; porous aluminum; foil ... See more keywords
Combination of antibody-coated, physical-based microfluidic chip with wave-shaped arrays for isolating circulating tumor cells
Sign Up to like & getrecommendations! Published in 2017 at "Biomedical Microdevices"
DOI: 10.1007/s10544-017-0202-3
Abstract: Circulating tumor cells (CTCs) are found in the peripheral blood of patients with metastatic cancers, which have critical significance in cancer prognosis and diagnostics. Enumeration is significantly valuable since number of CTCs is strongly correlated… read more here.
Keywords: wave shaped; microfluidic chip; tumor cells; chip ... See more keywords
Design and fabrication of portable continuous flow PCR microfluidic chip for DNA replication.
Sign Up to like & getrecommendations! Published in 2019 at "Biomedical microdevices"
DOI: 10.1007/s10544-019-0457-y
Abstract: The reasons for restricting continuous flow polymerase chain reaction (CF-PCR) microfluidic chip from lab to application are that it is not portable and requires costly external precision pumps for sample injection. Herein, we employed water… read more here.
Keywords: microfluidic chip; pcr microfluidic; dna replication; pcr ... See more keywords
Microvalve controlled multi-functional microfluidic chip for divisional cell co-culture.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2017.10.008
Abstract: Pneumatic micro-valve controlled microfluidic chip provides precise fluidic control for cell manipulation. In this paper, a multi-functional microfluidic chip was designed for three separate experiments: 1. Different cell lines were dispensed and cultured; 2. Three… read more here.
Keywords: microfluidic chip; functional microfluidic; cell culture; multi functional ... See more keywords
Isolinderalactone suppresses human glioblastoma growth and angiogenic activity in 3D microfluidic chip and in vivo mouse models.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.03.009
Abstract: Glioblastoma multiforme (GBM) is a lethal and highly vascular type of brain tumor. We previously reported that isolinderalactone enhances GBM apoptosis in vitro and in vivo, but its role in tumor angiogenesis is unknown. Here,… read more here.
Keywords: microfluidic chip; angiogenic activity; glioblastoma; activity ... See more keywords
Application of adaptive pressure-driven microfluidic chip in thyroid function measurement
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2021.01.008
Abstract: Abstract The improvement in accuracy of in vitro diagnosis has always been the focus of early screening of thyroid dysfunction. We constructed a microfluidic chip based on a polystyrene polymer substrate. Total triiodothyronine (TT3), total… read more here.
Keywords: application; function measurement; chip; microfluidic chip ... See more keywords
Experimental visualization of cyclopentane hydrate dissociation behavior in a microfluidic chip
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Engineering Science"
DOI: 10.1016/j.ces.2020.115937
Abstract: Abstract A concrete understanding of hydrate dissociation behavior is crucial for hydrate exploration and oil/gas transportation. A microfluidic chip has been used in this study to visualize cyclopentane (CP) hydrate dissociation. The results showed that… read more here.
Keywords: microfluidic chip; cyclopentane hydrate; dissociation; hydrate dissociation ... See more keywords