Intracellular Amyloid-β Detection from Human Brain Sections Using a Microfluidic Immunoassay in Tandem with MALDI-MS.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03825
Abstract: Alzheimer's disease (AD) currently affects more than 30 million people worldwide. The lack of understanding of AD's physiopathology limits the development of therapeutic and diagnostic tools. Soluble amyloid-β peptide (Aβ) oligomers that appear as intermediates… read more here.
Keywords: intracellular amyloid; brain; human brain; amyloid detection ... See more keywords
Bead Number Effect in a Magnetic-Beads-Based Digital Microfluidic Immunoassay
Sign Up to like & getrecommendations! Published in 2022 at "Biosensors"
DOI: 10.3390/bios12050340
Abstract: In a biomedical diagnosis with a limited sample volume and low concentration, droplet-based microfluidics, also called digital microfluidics, becomes a very attractive approach. Previously, our group developed a magnetic-beads-based digital microfluidic immunoassay with a bead… read more here.
Keywords: number; magnetic beads; based digital; microfluidic immunoassay ... See more keywords
Surface Hydrophilic Modification for Chip of Centrifugal Microfluidic Immunoassay System
Sign Up to like & getrecommendations! Published in 2022 at "Micromachines"
DOI: 10.3390/mi13060831
Abstract: The surface of a centrifugal microfluidic immunoassay system chip such as polymethyl methacrylate (PMMA) is often hydrophobic, which leads to problems such as poor liquid transfer efficiency and easy-to-block siphon channels, leading to bad fluid… read more here.
Keywords: immunoassay system; system; modification; centrifugal microfluidic ... See more keywords