Multitransgenic Porcine Fibroblasts are Protected from Immunoglobulin Binding and Complement Deposition in a Xeno-Microfluidic Model
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation"
DOI: 10.1097/01.tp.0000542707.45836.40
Abstract: Background One of the main issues that hamper xenotransplantation to be clinically feasible is humoral rejection. Xenoreactive antibodies, both natural or elicited, contribute significantly to rejection of xenotransplants by activation of complement and interactions with… read more here.
Keywords: complement deposition; bgr 4galnt2; immunoglobulin binding; complement ... See more keywords
Atherosclerosis on a Chip: A 3-Dimensional Microfluidic Model of Early Arterial Events in Human Plaques
Sign Up to like & getrecommendations! Published in 2024 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.124.321332
Abstract: BACKGROUND: Realistic reconstruction of the in vivo human atherosclerotic environment requires the coculture of different cell types arranged in atherosclerotic vessel–like structures with exposure to flow and circulating cells, presenting challenges for disease modeling. This… read more here.
Keywords: labeled human; microfluidic model; cell; smooth muscle ... See more keywords
Investigation of the Therapeutic Potential of New Antidiabetic Compounds Using Islet-on-a-Chip Microfluidic Model
Sign Up to like & getrecommendations! Published in 2022 at "Biosensors"
DOI: 10.3390/bios12050302
Abstract: Nowadays, diabetes mellitus is one of the most common chronic diseases in the world. Current research on the treatment of diabetes combines many fields of science, such as biotechnology, transplantology or engineering. Therefore, it is… read more here.
Keywords: chip microfluidic; microfluidic model; islet chip; chip ... See more keywords