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Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.am2020-3874
Abstract: The tumor microenvironment is defined by nutrient starvation, waste product accumulation, hypoxia, and acidosis, which collectively contribute towards immune exhaustion and suppression. Models that mimic the tumor microenvironment will be instrumental to develop new therapies…
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Keywords:
microscopy;
microfluidic models;
metabolic imaging;
cell ... See more keywords
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Published in 2017 at "Cancer immunology research"
DOI: 10.1158/2326-6074.tumimm16-b22
Abstract: Intravital imaging can be performed in mice and has proven extremely useful in uncovering the role of immune cells in cancer metastasis, but requires specialized expertise and equipment. In the last decade, microfluidic models have…
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Keywords:
cell extravasation;
extravasation;
cancer cell;
cancer ... See more keywords