Vascularized microfluidic organ-chips for drug screening, disease models and tissue engineering.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2018.03.011
Abstract: Vascularization of micro-tissues in vitro has enabled formation of tissues larger than those limited by diffusion with appropriate nutrient/gas exchange as well as waste elimination. Furthermore, angiocrine signaling from the vasculature may be essential in… read more here.
Keywords: organ chips; micro tissues; vascularized microfluidic; drug ... See more keywords
Microfluidic Organ-on-a-Chip Models of Human Intestine
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2017.12.010
Abstract: Microfluidic organ-on-a-chip models of human intestine have been developed and used to study intestinal physiology and pathophysiology. In this article, we review this field and describe how microfluidic Intestine Chips offer new capabilities not possible… read more here.
Keywords: human intestine; organ chip; models human; chip models ... See more keywords
Microfluidic Organ-Chips and Stem Cell Models in the Fight Against COVID-19
Sign Up to like & getrecommendations! Published in 2023 at "Circulation Research"
DOI: 10.1161/circresaha.122.321877
Abstract: SARS-CoV-2, the virus underlying COVID-19, has now been recognized to cause multiorgan disease with a systemic effect on the host. To effectively combat SARS-CoV-2 and the subsequent development of COVID-19, it is critical to detect,… read more here.
Keywords: cell; organ chips; stem cell; chips stem ... See more keywords
Microfluidic Organ-on-a-Chip System for Disease Modeling and Drug Development
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DOI: 10.3390/bios12060370
Abstract: An organ-on-a-chip is a device that combines micro-manufacturing and tissue engineering to replicate the critical physiological environment and functions of the human organs. Therefore, it can be used to predict drug responses and environmental effects… read more here.
Keywords: organ chip; chip system; disease modeling; drug ... See more keywords
Microfluidic Organ-on-a-Chip Devices for Liver Disease Modeling In Vitro
Sign Up to like & getrecommendations! Published in 2022 at "Micromachines"
DOI: 10.3390/mi13030428
Abstract: Mortality from liver disease conditions continues to be very high. As liver diseases manifest and progress silently, prompt measures after diagnosis are essential in the treatment of these conditions. Microfluidic organs-on-chip platforms have significant potential… read more here.
Keywords: diseases vitro; liver diseases; liver disease; microfluidic organ ... See more keywords