FLUIDOT: A Modular Microfluidic Platform for Single‐Cell Study and Retrieval, with Applications in Drug Tolerance Screening and Antibody Mining
Sign Up to like & getrecommendations! Published in 2023 at "Small Methods"
DOI: 10.1002/smtd.202201477
Abstract: Advancements in lab‐on‐a‐chip technologies have revolutionized the single‐cell analysis field. However, an accessible platform for in‐depth screening and specific retrieval of single cells, which moreover enables studying diverse cell types and performing various downstream analyses,… read more here.
Keywords: cell; platform; drug tolerance; microfluidic platform ... See more keywords
Application of β-glucuronidase-immobilised silica gel formulation to microfluidic platform for biotransformation of β-glucuronides
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology Letters"
DOI: 10.1007/s10529-018-2530-7
Abstract: ObjectiveTo improve the efficiency of reactions of β-glucuronidase (GUS)-assisted glucuronic acid (GluA) removal within a microfluidic system.Resultsβ-glucuronidase from Helix pomatia was immobilised and characterised in silica-based sol–gel monoliths. Efficiency of the GUS-doped silica monoliths was… read more here.
Keywords: microfluidic platform; application glucuronidase; immobilised silica; glucuronidase immobilised ... See more keywords
A customizable microfluidic platform for medium-throughput modeling of neuromuscular circuits
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2019.119537
Abstract: Neuromuscular circuits (NMCs) are vital for voluntary movement, and effective models of NMCs are needed to understand the pathogenesis of, as well as to identify effective treatments for, multiple diseases, including Duchenne’s muscular dystrophy and… read more here.
Keywords: microfluidic platform; medium throughput; neuromuscular circuits;
Microfluidic platform for synthesis and optimization of chitosan-coated magnetic nanoparticles in cisplatin delivery.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2021.118027
Abstract: In this study, magnetic core/chitosan shell Nanoparticles (NPs) containing cisplatin were synthesized via cisplatin complexation with tripolyphosphate as the chitosan crosslinker using two different procedures: a conventional batch flow method and a microfluidic approach. An… read more here.
Keywords: synthesis optimization; platform synthesis; microfluidic platform; delivery ... See more keywords
Conjugation of glucose oxidase and bilirubin oxidase bioelectrodes as biofuel cell in a finger-powered microfluidic platform
Sign Up to like & getrecommendations! Published in 2019 at "Electrochimica Acta"
DOI: 10.1016/j.electacta.2019.06.140
Abstract: Abstract In this study the development of a biofuel cell for potential application in microfluidics is described. The biocatalysts support is produced through vacuum-filtration of a Vulcan carbon black suspension resulting in flexible, paper-like electrodes.… read more here.
Keywords: bilirubin oxidase; glucose oxidase; oxidase; biofuel cell ... See more keywords
Rapid detection of olive oil blends using a paper-based portable microfluidic platform
Sign Up to like & getrecommendations! Published in 2021 at "Food Control"
DOI: 10.1016/j.foodcont.2021.107888
Abstract: Abstract This paper presents an application of a portable microfluidic platform based on a filter paper on which multi-walled carbon nanotubes were deposited to quickly determine the quality of olive oil by measuring electrical resistance.… read more here.
Keywords: portable microfluidic; paper; oil; platform ... See more keywords
Micro-bead immunoassays for the detection of IL6 and PDGF-2 proteins on a microfluidic platform, incorporating superhydrophobic passive valves
Sign Up to like & getrecommendations! Published in 2017 at "Microelectronic Engineering"
DOI: 10.1016/j.mee.2017.02.015
Abstract: A microfluidic platform optimized for bead-based immunoassays is presented. It uses a simple design that incorporates passive valves in the inlet and outlet of a microreactor. The superhydrophobic, passive valves are created by selective plasma… read more here.
Keywords: microfluidic platform; il6 pdgf; superhydrophobic passive; passive valves ... See more keywords
Construction of a microfluidic platform integrating online protein fractionation, denaturation, digestion, and peptide enrichment.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2020.121810
Abstract: Microfluidic system with multi-functional integration of high-throughput protein/peptide separation ability has great potential for improving the identification capacity of biological samples in proteomics. In this paper, a sample treatment platform was constructed by integrating reversed… read more here.
Keywords: microfluidic platform; fractionation denaturation; platform; denaturation digestion ... See more keywords
A Three-Dimensional Printed Inertial Microfluidic Platform for Isolation of Minute Quantities of Vital Mitochondria.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c03244
Abstract: We demonstrate a fast and easy-to-use three-dimensional printed microfluidic platform for mitochondria isolation from cell and tissue lysates based on inertial microfluidics. We present and quantify the quality of the isolated mitochondria by measuring the… read more here.
Keywords: microfluidic platform; dimensional printed; three dimensional; isolation ... See more keywords
Microfluidic Platform for High-Throughput Screening of Leach Chemistry.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b01413
Abstract: We demonstrate a microfluidic screening platform for studying thiosulfate leaching of Au in a transparent microchannel. The approach permits in situ (optical) monitoring of Au thickness, reduced reagent use, rapid optimization of reagent chemistry, screening… read more here.
Keywords: microfluidic platform; chemistry microfluidic; chemistry; leach ... See more keywords
Three-Dimensional Microfluidic Platform with Neural Organoids: Model System for Unraveling Synapses.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00654
Abstract: Unraveling the large number of various signals in the brain under the influence of physical and chemical cues that govern the formation of individual neurons, axons, dendrites, and their functional synapses during the development of… read more here.
Keywords: three dimensional; microfluidic platform; neural organoids; platform neural ... See more keywords