Enzyme mimetic microgel coating for endogenous nitric oxide mediated inhibition of platelet activation.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2021.05.143
Abstract: Nitric oxide (NO) continuously generated by healthy endothelium prevents platelet activation and maintains vascular homeostasis. However, when artificial surfaces, like of extracorporeal membrane oxygenator comes in contact with blood, protein adsorption and thereby platelet activation… read more here.
Keywords: nitric oxide; platelet activation; blood; microgel coating ... See more keywords
Endogenous Nitric Oxide-Releasing Microgel Coating Prevents Clot Formation on Oxygenator Fibers Exposed to In Vitro Blood Flow
Sign Up to like & getrecommendations! Published in 2022 at "Membranes"
DOI: 10.3390/membranes12010073
Abstract: Background: Clot formation on foreign surfaces of extracorporeal membrane oxygenation systems is a frequent event. Herein, we show an approach that mimics the enzymatic process of endogenous nitric oxide (NO) release on the oxygenator membrane… read more here.
Keywords: microgel coating; clot formation; endogenous nitric; formation ... See more keywords