Modulatory effect of IL‐1 inhibition following lipopolysaccharide‐induced neuroinflammation in neonatal microglia and astrocytes
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Developmental Neuroscience"
DOI: 10.1002/jdn.10179
Abstract: Inflammation‐induced white matter injury (WMI) in preterm infants is characterized by microglia activation, astrogliosis, oxidative stress and neurodevelopmental impairments. Microglia and astrocytes activation can be described under a broad spectrum of activation profile with extremes… read more here.
Keywords: microglia astrocytes; effect inhibition; microglia astrocyte; inhibition following ... See more keywords
Scavenger Receptor-A deficiency impairs immune response of microglia and astrocytes potentiating Alzheimer’s disease pathophysiology
Sign Up to like & getrecommendations! Published in 2018 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2017.12.007
Abstract: Late onset Alzheimer disease's (LOAD) main risk factor is aging. Although it is not well known which age-related factors are involved in its development, evidence points out to the involvement of an impaired amyloid-β (Aβ)… read more here.
Keywords: microglia astrocytes; response; alzheimer disease; scavenger receptor ... See more keywords
Isolation, culture, and downstream characterization of primary microglia and astrocytes from adult rodent brain and spinal cord
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2020.108742
Abstract: BACKGROUND Neuroimmunologists aspire to understand the interactions between neurons, microglia, and astrocytes in the CNS. To study these cells, researchers work with either immortalized cell lines or primary cells acquired from animal tissue. Primary cells… read more here.
Keywords: brain spinal; microglia astrocytes; microglia; spinal cord ... See more keywords
Differential response to lead toxicity in rat primary microglia and astrocytes
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.11.010
Abstract: ABSTRACT Lead (Pb) is one of the most widely studied occupational and environmental toxins. Chronic exposure to Pb affects neural function in the central nervous system (CNS). Glial cells in the CNS, such as microglia… read more here.
Keywords: primary microglia; microglia astrocytes; response; oxidative stress ... See more keywords
IFN-γ Producing Th1 Cells Induce Different Transcriptional Profiles in Microglia and Astrocytes
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2018.00352
Abstract: Autoreactive T cells that infiltrate into the central nervous system (CNS) are believed to have a significant role in mediating the pathology of neuroinflammatory diseases like multiple sclerosis. Their interaction with microglia and astrocytes in… read more here.
Keywords: microglia astrocytes; th1 cells; producing th1; profiles microglia ... See more keywords
The implication of a diversity of non-neuronal cells in disorders affecting brain networks
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.1015556
Abstract: In the central nervous system (CNS) neurons are classically considered the functional unit of the brain. Analysis of the physical connections and co-activation of neurons, referred to as structural and functional connectivity, respectively, is a… read more here.
Keywords: connectivity; microglia astrocytes; implication diversity; brain ... See more keywords
Microglia and astrocytes underlie neuroinflammation and synaptic susceptibility in autism spectrum disorder
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2023.1125428
Abstract: Autism spectrum disorder (ASD) is a common neurodevelopmental disorder with onset in childhood. The mechanisms underlying ASD are unclear. In recent years, the role of microglia and astrocytes in ASD has received increasing attention. Microglia… read more here.
Keywords: spectrum disorder; microglia astrocytes; microglia; autism spectrum ... See more keywords
Astrocytes Stimulate Microglial Proliferation and M2 Polarization In Vitro through Crosstalk between Astrocytes and Microglia
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22168800
Abstract: Microglia are resident immune cells of the central nervous system that act as brain-specific macrophages and are also known to regulate the innate immune functions of astrocytes through secretory molecules. This communication plays an important… read more here.
Keywords: microglia astrocytes; astrocytes microglia; microglial proliferation; polarization ... See more keywords
Mechanistic Insight into the Effects of Curcumin on Neuroinflammation-Driven Chronic Pain
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceuticals"
DOI: 10.3390/ph14080777
Abstract: Chronic pain is a persistent and unremitting condition that has immense effects on patients’ quality of life. Studies have shown that neuroinflammation is associated with the induction and progression of chronic pain. The activation of… read more here.
Keywords: microglia astrocytes; mechanistic insight; neuroinflammation; pain ... See more keywords