P.2.019: Brain region-specific control of microglia by adenosine A2A-adenosine receptors: uncoupling anxiety and cognition in female rodents
Sign Up to like & getrecommendations! Published in 2018 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.12.058
Abstract: Microglia morphology is critical for brain functioning and undergoes profound remodeling in neuropsychiatric diseases. Rats prenatally exposed to glucocorticoids (iuDEX), which become anxious and have cognitive deficits at adulthood, exhibit gender-specific changes in microglia morphology… read more here.
Keywords: iudex; anxiety; microglia morphology; anxiety cognition ... See more keywords
Quantitative microglia analyses reveal diverse morphologic responses in the rat cortex after diffuse brain injury
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-13581-z
Abstract: Determining regions of altered brain physiology after diffuse brain injury is challenging. Microglia, brain immune cells with ramified and dynamically moving processes, constantly surveil the parenchyma for dysfunction which, when present, results in a changed… read more here.
Keywords: microglia morphology; physiology; brain; diffuse brain ... See more keywords
Neonatal testosterone voids sexually differentiated microglia morphology and behavior
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1102068
Abstract: The involvement of immunity in psychiatric disorders, such as anxiety, is typified by the morphologic adaptation of microglia, immune cells of the brain, to anxiogenic stimuli. We previously reported sexually differentiated microglia morphology in adult… read more here.
Keywords: sexually differentiated; differentiated microglia; microglia morphology; morphology ... See more keywords