Lipid transporter Spns2 promotes microglia pro‐inflammatory activation in response to amyloid‐beta peptide
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DOI: 10.1002/glia.23558
Abstract: Accumulating evidence indicates that neuroinflammation contributes to the pathogenesis and exacerbation of neurodegenerative disorders, such as Alzheimer's disease (AD). Sphingosine‐1‐phosphate (S1P) is a pleiotropic bioactive lipid that regulates many pathophysiological processes including inflammation. We present… read more here.
Keywords: promotes microglia; microglia pro; inflammatory activation; spns2 ... See more keywords
Genome-Wide Screen and Validation of Microglia Pro-Inflammatory Mediators in Stroke
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DOI: 10.14336/ad.2020.0926
Abstract: Stroke activates microglia pro-inflammatory response that not only induces the early neuronal injuries but also causes the secondary brain infarction. Yet, the underlying mechanisms for how microglia become activated in stroke are still unknown. Here,… read more here.
Keywords: pro inflammatory; inflammatory response; mediators stroke; genome wide ... See more keywords