Sesamol alleviates manganese-induced neuroinflammation and cognitive impairment via regulating the microglial cGAS-STING/NF-κB pathway.
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DOI: 10.2139/ssrn.4249940
Abstract: Toxic effects of excessive manganese (Mn) from occupational or environmental exposure cause harm to human health. Excessive Mn exposure is intimately associated with neurodegeneration and cognitive dysfunction. Inflammatory responses mediated by microglia are essential contributors… read more here.
Keywords: sesamol; induced neurotoxicity; microglial cgas; sting pathway ... See more keywords