Manganese mobilizes microglial exosomes
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DOI: 10.1126/science.363.6423.137-w
Abstract: Inflammation Chronic occupational exposure to manganese is associated with the development of Parkinson's disease. Sarkar et al. found that exposure of primed microglia or mice to manganese increased the levels and activation of the NLRP3… read more here.
Keywords: manganese mobilizes; mobilizes microglial; microglial exosomes;
Intranasal Delivery of Gene-Edited Microglial Exosomes Improves Neurological Outcomes after Intracerebral Hemorrhage by Regulating Neuroinflammation
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DOI: 10.3390/brainsci13040639
Abstract: Neural inflammatory response is a crucial pathological change in intracerebral hemorrhage (ICH) which accelerates the formation of perihematomal edema and aggravates neural cell death. Although surgical and drug treatments for ICH have advanced rapidly in… read more here.
Keywords: microglial exosomes; intranasal delivery; neuroinflammation; brain ... See more keywords