Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits.
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DOI: 10.1126/sciadv.abm2545
Abstract: Parvalbumin-positive (PV+) interneurons play a critical role in maintaining circuit rhythm in the brain, and their reduction is implicated in autism spectrum disorders. Animal studies demonstrate that maternal immune activation (MIA) leads to reduced PV+… read more here.
Keywords: parvalbumin positive; microglial gpr56; maternal immune; interneuron ... See more keywords