APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge
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DOI: 10.1101/2022.05.17.492361
Abstract: The E4 allele of Apolipoprotein E (APOE) is associated with both metabolic dysfunction and a heightened pro-inflammatory response – two findings that may be intrinsically linked through the concept of immunometabolism. Here, we combined bulk,… read more here.
Keywords: microglial immunometabolism; inflammatory challenge; pathology; apoe ... See more keywords