Microglial metabolic flexibility supports immune surveillance of the brain parenchyma
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-15267-z
Abstract: Microglia are highly motile cells that continuously monitor the brain environment and respond to damage-associated cues. While glucose is the main energy substrate used by neurons in the brain, the nutrients metabolized by microglia to… read more here.
Keywords: immune surveillance; surveillance; flexibility supports; microglial metabolic ... See more keywords
Microglial metabolic reconfiguration provides a new strategy for the treatment of Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2023 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.367842
Abstract: Alzheimer ’s disease (AD) shares multiple characteristics of metabolic diseases: AD is an age-associated neurodegenerative disease characterized by progressive loss of memory and cognitive functions, which is classically manifested by the deposition of β-amyloid (Aβ)… read more here.
Keywords: reconfiguration provides; provides new; disease; alzheimer disease ... See more keywords