Definition of a mouse microglial subset that regulates neuronal development and proinflammatory responses in the brain
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2116241119
Abstract: Significance CD11c+ microglia enriched for osteopontin (OPN) expression appear at distinct stages of brain development, aging, and several neurodegenerative disorders. Whether coexpression of CD11c and OPN results from microglial activation or represents a part of… read more here.
Keywords: cd11c; definition; microglial subset; development ... See more keywords
Definition of the contribution of an Osteopontin-producing CD11c+ microglial subset to Alzheimer's disease.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2218915120
Abstract: Alzheimer's disease (AD) is the most common form of incurable dementia and represents a critical public health issue as the world's population ages. Although microglial dysregulation is a cardinal feature of AD, the extensive heterogeneity… read more here.
Keywords: microglial subset; disease; alzheimer disease; producing cd11c ... See more keywords