Articles with "microglial transcriptional" as a keyword



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Diverse human astrocyte and microglial transcriptional responses to Alzheimer’s pathology

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Published in 2021 at "Acta Neuropathologica"

DOI: 10.1007/s00401-021-02372-6

Abstract: To better define roles that astrocytes and microglia play in Alzheimer’s disease (AD), we used single-nuclei RNA-sequencing to comprehensively characterise transcriptomes in astrocyte and microglia nuclei selectively enriched during isolation post-mortem from neuropathologically defined AD… read more here.

Keywords: microglial transcriptional; diverse human; astrocytes microglia; pathology ... See more keywords