Defining the pig microglial transcriptome reveals its core signature, regional heterogeneity, and similarity with human and rodent microglia
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DOI: 10.1002/glia.24274
Abstract: Microglia play key roles in brain homeostasis as well as responses to neurodegeneration and neuroinflammatory processes caused by physical disease and psychosocial stress. The pig is a physiologically relevant model species for studying human neurological… read more here.
Keywords: signature; defining pig; regional heterogeneity; microglial transcriptome ... See more keywords
The temporal and spatial signature of microglial transcriptome in neuropathic pain
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DOI: 10.1097/wnr.0000000000001899
Abstract: Microglial activation following peripheral nerve injury is crucial for neuropathic pain (NP) development; however, studies on time-specific and spatial characteristics of microglial transcriptome are scarce. Firstly, we comparatively analysed microglial transcriptome of different brain regions… read more here.
Keywords: microglial transcriptome; neuropathic pain; pain; nerve injury ... See more keywords