Clinical and prognostic values of urinary alpha1-microglobulin as a tubular marker in acute heart failure.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2021.06.041
Abstract: BACKGROUND Although urinary alpha-1-microglobulin has been used as a marker of tubular dysfunction, its clinical and prognostic values in patients with acute heart failure have not been validated. METHODS We analyzed 623 patients (74 ± 13 years old,… read more here.
Keywords: alpha microglobulin; microglobulin; acute heart; heart failure ... See more keywords
Ratiometric quantification of β2-microglobulin antigen in human serum based on elemental labeling strategy.
Sign Up to like & getrecommendations! Published in 2018 at "Talanta"
DOI: 10.1016/j.talanta.2018.07.003
Abstract: Ratiometric quantification for competitive immunoassay based on internal standard element detection utilizing inductively coupled plasma mass spectrometry (ICP-MS) as multiplex readout has been demonstrated. The Beta-2-microglobulin (β2-MG) associated with clinical diseases was detected by Y-labeled… read more here.
Keywords: ratiometric quantification; serum; microglobulin; antigen ... See more keywords
Increased β-Sheet Dynamics and D-E Loop Repositioning Are Necessary for Cu(II)-Induced Amyloid Formation by β-2-Microglobulin.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry"
DOI: 10.1021/acs.biochem.6b01198
Abstract: β-2-Microglobulin (β2m) forms amyloid fibrils in the joints of patients undergoing dialysis treatment as a result of kidney failure. One of the ways in which β2m can be induced to form amyloid fibrils in vitro… read more here.
Keywords: formation; sheet; microglobulin; amyloid formation ... See more keywords
The structure of a β2-microglobulin fibril suggests a molecular basis for its amyloid polymorphism
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-06761-6
Abstract: All amyloid fibrils contain a cross-β fold. How this structure differs in fibrils formed from proteins associated with different diseases remains unclear. Here, we combine cryo-EM and MAS-NMR to determine the structure of an amyloid… read more here.
Keywords: fibril suggests; microglobulin; structure; structure microglobulin ... See more keywords
MO523PATIENTS FROM COVID-19 MOSTLY RECOVER FROM TUBULAR PROTEINURIA AND ACUTE KIDNEY INJURY AFTER HOSPITAL DISCHARGE
Sign Up to like & getrecommendations! Published in 2021 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfab087.0043
Abstract: Abstract Background and Aims Proteinuria, hematuria and acute kidney injury (AKI) are frequently observed in hospitalized patients with COVID-19. However, few data are available on these parameters after hospital discharge. Method This retrospective, observational and… read more here.
Keywords: hospitalization; hospital discharge; discharge; acute kidney ... See more keywords
Convection volume, β2‐microglobulin and α1‐microglobulin reduction ratios, and body composition in pre‐dilution online haemodiafiltration
Sign Up to like & getrecommendations! Published in 2022 at "Nephrology"
DOI: 10.1111/nep.14038
Abstract: The effect of convection volume (CV) in patients on pre‐dilution online haemodiafiltration (Pre‐OL‐HDF) was evaluated. read more here.
Keywords: online haemodiafiltration; pre dilution; microglobulin; convection volume ... See more keywords
α1‐ and β2‐Microglobulin reduction ratios and survival in patients on predilution online haemodiafiltration
Sign Up to like & getrecommendations! Published in 2022 at "Nephrology"
DOI: 10.1111/nep.14125
Abstract: β2‐Microglobulin (β2‐MG) and α1‐microglobulin (α1‐MG) have molecular weights of 11,800 and 33,000 Da, respectively. We studied the α1‐MG and β2‐MG reduction ratios (RRs) and survival in patients on predilution online haemodiafiltration (Pre‐OL‐HDF). read more here.
Keywords: predilution online; patients predilution; online haemodiafiltration; reduction ratios ... See more keywords
High serum β2‐microglobulin is a significant predictor of mortality in maintenance hemodialysis patients
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in Dialysis"
DOI: 10.1111/sdi.13128
Abstract: Beta2‐microglobulin, a novel marker of kidney function, predicts kidney failure and mortality in the general population. However, few studies have evaluated the association of serum β2‐MG level with clinical outcome in maintenance hemodialysis (MHD) patients. read more here.
Keywords: high serum; mortality; microglobulin; maintenance hemodialysis ... See more keywords
Role of β2-microglobulin in postoperative cognitive decline.
Sign Up to like & getrecommendations! Published in 2017 at "Biomarkers in medicine"
DOI: 10.2217/bmm-2016-0274
Abstract: AIM β2-microglobulin (β2M) was proved to affect hippocampal functions in mice. MATERIALS & METHODS Seventy-one patients undergoing aortic valve replacement were analyzed in prospective observational study. Kidney biomarkers and Mini Mental State Examinations (MMSEs) were… read more here.
Keywords: role microglobulin; postoperative cognitive; microglobulin postoperative; microglobulin ... See more keywords
Raised β2-Microglobulin as a Surrogate Marker in Non-Secretory Multiple Myeloma
Sign Up to like & getrecommendations! Published in 2017 at "Bangladesh Journal of Medical Science"
DOI: 10.3329/bjms.v16i1.31146
Abstract: Multiple myeloma is a neoplasm of plasma cells in the bone marrow. It is characterised by lytic lesions in the bones, marrow plasmacytosis and presence of M protein in serum and/or urine. Serum β2 microglobulin… read more here.
Keywords: non secretory; myeloma; raised microglobulin; multiple myeloma ... See more keywords
Hippocampal β2‑microglobulin mediates sepsis‑induced cognitive impairment.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular medicine reports"
DOI: 10.3892/mmr.2018.8858
Abstract: Acute brain dysfunction is a frequent complication in sepsis patients and is associated with long‑term neurocognitive consequences and increased mortality, yet the underlying mechanism remains unclear. Emerging evidence has suggested that β2‑microglobulin [a component of… read more here.
Keywords: mediates sepsis; induced cognitive; cognitive impairment; microglobulin ... See more keywords