Activation of HIF-1α and its downstream targets in rat hippocampus after long-term simulated microgravity exposure.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2016.12.078
Abstract: Microgravity has many detrimental impact on brain functions, however the underlying mechanism remain unclear. In present study, 28 days of tail-suspension (30°) was used to simulate microgravity in rats. We showed that oxidative stress in… read more here.
Keywords: hif; downstream targets; microgravity exposure; simulated microgravity ... See more keywords
Muscle-specific atrophy of the lower limb musculature in responseto simulated microgravity exposure in women.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00483.2025
Abstract: Despite the increased involvement of women in spaceflight missions, the efforts to understand changes in skeletal muscle health in women with microgravity exposure have been limited. The goal of the current investigation was to expand… read more here.
Keywords: muscle; simulated microgravity; microgravity exposure; microgravity ... See more keywords
Simulated microgravity exposure markedly attenuates the baroreflex total loop gain and induces orthostatic hypotension in male rats
Sign Up to like & getrecommendations! Published in 2025 at "Physiological Reports"
DOI: 10.14814/phy2.70637
Abstract: Autonomic dysfunction is recognized as the central mechanism of orthostatic hypotension after microgravity exposure. Because the arterial baroreflex regulates arterial pressure (AP) via sympathetic nerve activity (SNA), we investigated the systematic baroreflex function under simulated… read more here.
Keywords: orthostatic hypotension; gain; total loop; simulated microgravity ... See more keywords