Modeling Patient-Specific Muscular Dystrophy Phenotypes and Therapeutic Responses in Reprogrammed Myotubes Engineered on Micromolded Gelatin Hydrogels
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DOI: 10.3389/fcell.2022.830415
Abstract: In vitro models of patient-derived muscle allow for more efficient development of genetic medicines for the muscular dystrophies, which often present mutation-specific pathologies. One popular strategy to generate patient-specific myotubes involves reprogramming dermal fibroblasts to… read more here.
Keywords: patient specific; gelatin hydrogels; muscle; muscular dystrophy ... See more keywords