Multifunctional Inverse Opal Microneedle Arrays for Drug Delivery and Monitoring.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202201889
Abstract: Microneedle arrays (MNs) have a demonstrated value in transdermal drug delivery systems. Attempts to this technology focus on the generation of functional MNs to achieve intelligent drug delivery. Here, multifunctional inverse opal microneedle (IOMN) arrays… read more here.
Keywords: microneedle arrays; iomns; multifunctional inverse; drug delivery ... See more keywords
Conductive Polymer-Coated 3D Printed Microneedles: Biocompatible Platforms for Minimally Invasive Biosensing Interfaces.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202206301
Abstract: Conductive polymeric microneedle (MN) arrays as biointerface materials show promise for the minimally invasive monitoring of analytes in biodevices and wearables. There is increasing interest in microneedles as electrodes for biosensing, but efforts have been… read more here.
Keywords: minimally invasive; conductive polymer; polymer based; microneedle arrays ... See more keywords
Drug-coated microneedles for rapid and painless local anesthesia
Sign Up to like & getrecommendations! Published in 2017 at "Biomedical Microdevices"
DOI: 10.1007/s10544-016-0144-1
Abstract: This study showed that drug-coated PLLA (Poly (L-lactide)) microneedle arrays can induce rapid and painless local anesthesia. Microneedle arrays were fabricated using a micro-molding technique, and the needle tips were coated with 290.6 ± 45.9 μg of lidocaine,… read more here.
Keywords: microneedle arrays; drug coated; lidocaine; local anesthesia ... See more keywords
Mesoporous Silica Nanoparticle-Coated Microneedle Arrays for Intradermal Antigen Delivery
Sign Up to like & getrecommendations! Published in 2017 at "Pharmaceutical Research"
DOI: 10.1007/s11095-017-2177-4
Abstract: PurposeTo develop a new intradermal antigen delivery system by coating microneedle arrays with lipid bilayer-coated, antigen-loaded mesoporous silica nanoparticles (LB-MSN-OVA).MethodsSynthesis of MSNs with 10-nm pores was performed and the nanoparticles were loaded with the model… read more here.
Keywords: msn ova; intradermal antigen; microneedle arrays; delivery ... See more keywords
Molecular Imprinted Polymers on Microneedle Arrays for Point of Care Transdermal Sampling and Sensing of Inflammatory Biomarkers
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c04789
Abstract: The skin interstitial fluid (ISF) contains biomarkers that complement other biofluids such as blood, sweat, saliva, and urine. It can be sampled in a minimally invasive manner and used either for point of care testing… read more here.
Keywords: point care; microneedle arrays; isf; imprinted polymers ... See more keywords
Dissolving Microneedle Arrays as a Hepatitis B Vaccine Delivery System Adjuvanted by APC-Targeted Poly (Lactic-co-Glycolic Acid) (PLGA) Nanoparticles
Sign Up to like & getrecommendations! Published in 2023 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02473-9
Abstract: The objective of this study is to develop a new hepatitis B surface antigen (HBsAg) delivery system by coating soluble microneedle arrays with mannose-modified PLGA nanoparticles (MNPs). MNPs of different sizes were synthesized. The effects… read more here.
Keywords: hbsag; microneedle arrays; delivery system; plga nanoparticles ... See more keywords
Innovative Fabrication of Hollow Microneedle Arrays Enabling Blood Sampling with a Self-Powered Microfluidic Patch
Sign Up to like & getrecommendations! Published in 2023 at "Micromachines"
DOI: 10.3390/mi14030615
Abstract: Microneedles are gaining a lot of attention in the context of sampling cutaneous biofluids such as capillary blood. Their minimal invasiveness and user-friendliness make them a prominent substitute for venous puncture or finger-pricking. Although the… read more here.
Keywords: microneedle arrays; fabrication; hollow microneedle; self powered ... See more keywords
The Effect of 3D Printing Tilt Angle on the Penetration of 3D-Printed Microneedle Arrays
Sign Up to like & getrecommendations! Published in 2023 at "Micromachines"
DOI: 10.3390/mi14061157
Abstract: Microneedle arrays (MNAs) are emerging devices that are mainly used for drug delivery and diagnostic applications through the skin. Different methods have been used to fabricate MNAs. Recently developed fabrication methods based on 3D printing… read more here.
Keywords: skin; penetration; microneedle arrays; printing tilt ... See more keywords
Performance Enhancement of PLA-Based Blend Microneedle Arrays through Shish-Kebab Structuring Strategy in Microinjection Molding
Sign Up to like & getrecommendations! Published in 2023 at "Polymers"
DOI: 10.3390/polym15102234
Abstract: Poly(lactic acid) (PLA) microneedles have been explored extensively, but the current regular fabrication strategy, such as thermoforming, is inefficient and poorly conformable. In addition, PLA needs to be modified as the application of microneedle arrays… read more here.
Keywords: pla; shish kebab; microneedle arrays; blend ... See more keywords
Bioimaging of Dissolvable Microneedle Arrays: Challenges and Opportunities
Sign Up to like & getrecommendations! Published in 2022 at "Research"
DOI: 10.34133/2022/9758491
Abstract: The emergence of microneedle arrays (MNAs) as a novel, simple, and minimally invasive administration approach largely addresses the challenges of traditional drug delivery. In particular, the dissolvable MNAs act as a promising, multifarious, and well-controlled… read more here.
Keywords: microneedle arrays; arrays challenges; bioimaging dissolvable; dissolvable microneedle ... See more keywords