Articles with "microneedle patch" as a keyword



Reservoir Microneedle Patch Mitigates Postsurgical Atrial Fibrillation

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Published in 2024 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202312525

Abstract: Oral amiodarone for 3–6 months is commonly required for the prevention and treatment of atrial fibrillation (AF) after surgical ablation of refractory AF. However, clinical data show that oral administration is likely to cause systemic… read more here.

Keywords: microneedle patch; oral administration; reservoir microneedle; atrial fibrillation ... See more keywords

Recruitment and Collection of Dermal Interstitial Fluid Using a Microneedle Patch.

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Published in 2019 at "Advanced healthcare materials"

DOI: 10.1002/adhm.201801262

Abstract: Interstitial fluid (ISF) that surrounds cells in tissues of the body is a novel source of biomarker that complements conventional sources like blood, urine, and saliva. To overcome difficulties in harvesting ISF, a minimally invasive,… read more here.

Keywords: isf; interstitial fluid; patch; microneedle patch ... See more keywords

Peripheral Microneedle Patch for First‐Aid Hemostasis

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Published in 2022 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202201697

Abstract: Despite the minimized puncture sizes and high efficiency, microneedle (MN) patches have not been used to inject hemostatic drugs into bleeding wounds because they easily destroy capillaries when a tissue is pierced. In this study,… read more here.

Keywords: microneedle patch; hemostasis; patch first; peripheral microneedle ... See more keywords

Microneedle Patch for Painless Intradermal Collection of Interstitial Fluid Enabling Multianalyte Measurement of Small Molecules, SARS‐CoV‐2 Antibodies, and Protein Profiling

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Published in 2023 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202202564

Abstract: Blood sampling is a common practice to monitor health, but it entails a series of drawbacks for patients including pain and discomfort. Thus, there is a demand for more convenient ways to obtain samples. Modern… read more here.

Keywords: microneedle patch; cov antibodies; painless; interstitial fluid ... See more keywords

Enhancing Infected Diabetic Wound Healing through Multifunctional Nanocomposite‐Loaded Microneedle Patch: Inducing Multiple Regenerative Sites

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Published in 2024 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202301985

Abstract: Infected diabetic wound (DW) presents a prolonged and challenging healing process within the field of regenerative medicine. The effectiveness of conventional drug therapies is hindered by their limited ability to reach deep tissues and promote… read more here.

Keywords: patch; diabetic wound; wound healing; microneedle patch ... See more keywords

Polyphenol‐Modified Mg−Zn Layered Hydroxide‐Contained Microneedle Patch Enhance Mucosal Repair by Remolding Diabetic Oral Microenvironment

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Published in 2025 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202403883

Abstract: Diabetic oral ulcers pose a significant challenge in healing due to persistent inflammation. Despite local therapeutic interventions remaining the primary mode of treatment, the dynamic nature of the oral cavity, characterized by continuous muscular activity… read more here.

Keywords: layered hydroxide; oral ulcers; microneedle patch; modified layered ... See more keywords

Grooved Microneedle Patch Augments Adoptive T Cell Therapy Against Solid Tumors via Diverting Regulatory T Cells

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Published in 2024 at "Advanced Materials"

DOI: 10.1002/adma.202401667

Abstract: The efficacy of adoptive T cell therapy (ACT) for the treatment of solid tumors remains challenging. In addition to the poor infiltration of effector T (Teff) cells limited by the physical barrier surrounding the solid… read more here.

Keywords: cell therapy; grooved microneedle; solid tumors; cell ... See more keywords

Fabrication of sponge-forming microneedle patch for rapidly sampling interstitial fluid for analysis.

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Published in 2019 at "Biomedical microdevices"

DOI: 10.1007/s10544-019-0413-x

Abstract: Microneedle (MN) patch has been used for collecting dermal interstitial fluid (ISF) containing biomarkers from patients with safety, pain-free and easy-to-use manner. However, long sampling time for biomarkers analysis still poses a significant challenge. Here,… read more here.

Keywords: sponge forming; analysis; patch; interstitial fluid ... See more keywords
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Transdermal delivery of a somatostatin receptor type 2 antagonist using microneedle patch technology for hypoglycemia prevention.

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Published in 2021 at "Drug delivery and translational research"

DOI: 10.1007/s13346-021-00944-3

Abstract: Hypoglycemia is a serious and potentially fatal complication experienced by people with insulin-dependent diabetes. The complication is usually caused by insulin overdose, skipping meals, and/or excessive physical activities. In type 1 diabetes (T1D), on top… read more here.

Keywords: delivery; patch; hypoglycemia; prl 2903 ... See more keywords

A boosting skin vaccination with dissolving microneedle patch encapsulating M2e vaccine broadens the protective efficacy of conventional influenza vaccines

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Published in 2017 at "Journal of Controlled Release"

DOI: 10.1016/j.jconrel.2017.06.017

Abstract: Abstract The biodegradable microneedle patch (MNP) is a novel technology for vaccine delivery that could improve the immunogenicity of vaccines. To broaden the protective efficiency of conventional influenza vaccines, a new 4M2e‐tFliC fusion protein construct… read more here.

Keywords: tflic mnp; influenza vaccines; 4m2e tflic; conventional influenza ... See more keywords

Colloidal crystal microneedle patch for glucose monitoring

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Published in 2020 at "Nano Today"

DOI: 10.1016/j.nantod.2020.100984

Abstract: Abstract Blood glucose monitoring is a daily routine of people with type 1 or advanced type 2 diabetes. Efforts on minimizing invasiveness, improving portability, and enhancing sustainability of the existing glucose monitoring devices are demanding… read more here.

Keywords: colloidal crystal; microneedle patch; glucose monitoring; patch ... See more keywords