Recruitment and Collection of Dermal Interstitial Fluid Using a Microneedle Patch.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201801262
Abstract: Interstitial fluid (ISF) that surrounds cells in tissues of the body is a novel source of biomarker that complements conventional sources like blood, urine, and saliva. To overcome difficulties in harvesting ISF, a minimally invasive,… read more here.
Keywords: isf; interstitial fluid; patch; microneedle patch ... See more keywords
Peripheral Microneedle Patch for First‐Aid Hemostasis
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201697
Abstract: Despite the minimized puncture sizes and high efficiency, microneedle (MN) patches have not been used to inject hemostatic drugs into bleeding wounds because they easily destroy capillaries when a tissue is pierced. In this study,… read more here.
Keywords: microneedle patch; hemostasis; patch first; peripheral microneedle ... See more keywords
Microneedle Patch for Painless Intradermal Collection of Interstitial Fluid Enabling Multianalyte Measurement of Small Molecules, SARS‐CoV‐2 Antibodies, and Protein Profiling
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202564
Abstract: Blood sampling is a common practice to monitor health, but it entails a series of drawbacks for patients including pain and discomfort. Thus, there is a demand for more convenient ways to obtain samples. Modern… read more here.
Keywords: microneedle patch; cov antibodies; painless; interstitial fluid ... See more keywords
Fabrication of sponge-forming microneedle patch for rapidly sampling interstitial fluid for analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Biomedical microdevices"
DOI: 10.1007/s10544-019-0413-x
Abstract: Microneedle (MN) patch has been used for collecting dermal interstitial fluid (ISF) containing biomarkers from patients with safety, pain-free and easy-to-use manner. However, long sampling time for biomarkers analysis still poses a significant challenge. Here,… read more here.
Keywords: sponge forming; analysis; patch; interstitial fluid ... See more keywords
Transdermal delivery of a somatostatin receptor type 2 antagonist using microneedle patch technology for hypoglycemia prevention.
Sign Up to like & getrecommendations! Published in 2021 at "Drug delivery and translational research"
DOI: 10.1007/s13346-021-00944-3
Abstract: Hypoglycemia is a serious and potentially fatal complication experienced by people with insulin-dependent diabetes. The complication is usually caused by insulin overdose, skipping meals, and/or excessive physical activities. In type 1 diabetes (T1D), on top… read more here.
Keywords: delivery; patch; hypoglycemia; prl 2903 ... See more keywords
A boosting skin vaccination with dissolving microneedle patch encapsulating M2e vaccine broadens the protective efficacy of conventional influenza vaccines
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2017.06.017
Abstract: Abstract The biodegradable microneedle patch (MNP) is a novel technology for vaccine delivery that could improve the immunogenicity of vaccines. To broaden the protective efficiency of conventional influenza vaccines, a new 4M2e‐tFliC fusion protein construct… read more here.
Keywords: tflic mnp; influenza vaccines; 4m2e tflic; conventional influenza ... See more keywords
Colloidal crystal microneedle patch for glucose monitoring
Sign Up to like & getrecommendations! Published in 2020 at "Nano Today"
DOI: 10.1016/j.nantod.2020.100984
Abstract: Abstract Blood glucose monitoring is a daily routine of people with type 1 or advanced type 2 diabetes. Efforts on minimizing invasiveness, improving portability, and enhancing sustainability of the existing glucose monitoring devices are demanding… read more here.
Keywords: colloidal crystal; microneedle patch; glucose monitoring; patch ... See more keywords
Wearable All-Solid-State Potentiometric Microneedle Patch for Intradermal Potassium Detection.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b04877
Abstract: A new analytical all-solid-state platform for intradermal potentiometric detection of potassium in interstitial fluid is presented here. Solid microneedles are modified with different coatings and polymeric membranes to prepare both the potassium-selective electrode and reference… read more here.
Keywords: solid state; microneedle patch; potassium; detection ... See more keywords
Galunisertib-Loaded Gelatin Methacryloyl Hydrogel Microneedle Patch for Cardiac Repair after Myocardial Infarction
Sign Up to like & getrecommendations! Published in 2022 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.2c05352
Abstract: Uncontrolled and excessive fibrosis after myocardial infarction (MI) in the peri-infarct zone leads to left ventricular remodeling and deterioration of cardiac function. Inhibiting fibroblast activation during the mature phase of cardiac repair improves cardiac remodeling… read more here.
Keywords: microneedle patch; myocardial infarction; gelatin methacryloyl; cardiac repair ... See more keywords
Conductive Microneedle Patch with Electricity-Triggered Drug Release Performance for Atopic Dermatitis Treatment.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c05952
Abstract: Atopic dermatitis (AD) is a chronic inflammatory skin disease that seriously affects the life quality of patients. Topical administration of glucocorticoids is considered to be the most effective anti-inflammatory treatment. However, due to the barrier… read more here.
Keywords: treatment; drug; drug release; microneedle patch ... See more keywords
Dissolving Microneedle Patch Integrated with Microspheres for Long-Acting Hair Regrowth Therapy.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c22814
Abstract: Androgenetic alopecia (AGA) is the most common type of progressive hair loss in both men and women that severely reduces life quality and affects patients' self-esteem. Due to the shortcomings of traditional therapeutic formulations (e.g.,… read more here.
Keywords: microneedle patch; microspheres long; hair; patch integrated ... See more keywords