Microneedle Patches with O2 Propellant for Deeply and Fast Delivering Photosensitizers: Towards Improved Photodynamic Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202202591
Abstract: Photodynamic therapy (PDT) is an emerging technique for treating tumors. Especially, topical administration of photosensitizers (PSs) is more favorable for superficial tumor treatments with low systematic phototoxicity. Yet, ineffective migration of PSs to targeted tumor… read more here.
Keywords: microneedle patches; patches propellant; photodynamic therapy; improved pdt ... See more keywords
Microneedle Patches with Antimicrobial and Immunomodulating Properties for Infected Wound Healing.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202300576
Abstract: Treatment of infected wounds remains a challenge owing to antibiotic resistance; thus, developing smart biomaterials for the healing of infected wounds is urgently needed. In this study, a microneedle (MN) patch system with antimicrobial and… read more here.
Keywords: wound healing; microneedle patches; patches antimicrobial; infected wound ... See more keywords
Spatiotemporal Catalytic Nanozymes Microneedle Patches with Opposite Properties for Wound Management.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202302347
Abstract: Reactive oxygen species (ROS)-mediated biological catalysis involves serial programmed enzymatic reactions and plays an important part against infectious diseases; while the spatiotemporal control of catalytic treatment to break the limitations of the disease microenvironment is… read more here.
Keywords: catalytic nanozymes; microneedle patches; opposite properties; patches opposite ... See more keywords
Stimuli-responsive transdermal microneedle patches
Sign Up to like & getrecommendations! Published in 2021 at "Materials Today"
DOI: 10.1016/j.mattod.2021.03.012
Abstract: Abstract Microneedle (MN) patches consisting of miniature needles have emerged as a promising tool to perforate the stratum corneum and translocate biomolecules into the dermis in a minimally invasive manner. Stimuli-responsive MN patches represent emerging… read more here.
Keywords: stimuli responsive; microneedle patches; transdermal microneedle; responsive transdermal ... See more keywords
Effect of Surface Interactions on Microsphere Loading in Dissolving Microneedle Patches
Sign Up to like & getrecommendations! Published in 2022 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.2c05795
Abstract: Microneedle (MN) patches enable simple self-administration of drugs via the skin. In this study, we sought to deliver drug-loaded microspheres (MSs) using MN patches and found that the poly(lactic-co-glycolic acid) (PLGA) MSs failed to localize… read more here.
Keywords: surface interactions; surface; microneedle patches; hydrophobic interactions ... See more keywords
Detachable Microneedle Patches Deliver Mesenchymal Stromal Cell Factor-Loaded Nanoparticles for Cardiac Repair.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.2c03060
Abstract: Intramyocardial injection is a direct and efficient approach to deliver therapeutics to the heart. However, the injected volume must be very limited, and there is injury to the injection site and leakage issues during heart… read more here.
Keywords: detachable microneedle; patches deliver; mesenchymal stromal; microneedle patches ... See more keywords
Composite-dissolving microneedle patches for chemotherapy and photothermal therapy in superficial tumor treatment.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials science"
DOI: 10.1039/c8bm00005k
Abstract: A combination of chemotherapy and photothermal therapy (PTT) has emerged as a promising strategy for cancer therapy. To ensure that the chemotherapeutic drug and photothermal agent can be simultaneously delivered to the tumor site to… read more here.
Keywords: chemotherapy photothermal; microneedle patches; composite dissolving; therapy ... See more keywords
Synthesis and characterization of ionic liquid microneedle patches with different carbon chain lengths for antibacterial application.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d1bm01661j
Abstract: The prevention of bacterial infection is becoming more and more important in clinical medicine. Ionic liquids (ILs) can change the structure in an almost infinite way to actively antagonize pathogenic microorganism strains. The current biological… read more here.
Keywords: chain lengths; carbon chain; different carbon; microneedle patches ... See more keywords
Fast Customization of Hollow Microneedle Patches for Insulin Delivery
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Bioprinting"
DOI: 10.18063/ijb.v8i2.553
Abstract: Hollow microneedle patches (HMNPs) have great promise for efficient and precise transdermal drug delivery in a painless manner. Currently, the clinical application of HMNPs is restricted by its complex manufacturing processes. Here, we use a… read more here.
Keywords: hmnps; microneedle patches; fast customization; hollow microneedle ... See more keywords
Simvastatin Loaded Dissolvable Microneedle Patches with Improved Pharmacokinetic Performance
Sign Up to like & getrecommendations! Published in 2022 at "Micromachines"
DOI: 10.3390/mi13081304
Abstract: Microneedle patches (MNPs) are one of the emerging approaches for drug delivery involving minimal invasion and improved skin penetration of macro- and micro-entities. Herein, we report dissolvable microneedle patches (dMNPs) as a novel tool for… read more here.
Keywords: microneedle patches; simvastatin loaded; dissolvable microneedle; loaded dissolvable ... See more keywords
Low Adenovirus Vaccine Doses Administered to Skin Using Microneedle Patches Induce Better Functional Antibody Immunogenicity as Compared to Systemic Injection
Sign Up to like & getrecommendations! Published in 2021 at "Vaccines"
DOI: 10.3390/vaccines9030299
Abstract: Adenovirus-based vaccines are demonstrating promising clinical potential for multiple infectious diseases, including COVID-19. However, the immunogenicity of the vector itself decreases its effectiveness as a boosting vaccine due to the induction of strong anti-vector neutralizing… read more here.
Keywords: vaccine doses; adenovirus vaccine; low adenovirus; antibody ... See more keywords