ViroSpot microneutralization assay for antigenic characterization of human influenza viruses.
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2016.11.060
Abstract: The hemagglutination inhibition (HI) assay has been used for the antigenic characterization of influenza viruses for decades. However, the majority of recent seasonal influenza A viruses of the H3N2 subtype has lost the capacity to… read more here.
Keywords: influenza viruses; antigenic characterization; influenza; virospot microneutralization ... See more keywords
Improving ability of RSV microneutralization assay to detect G-specific and cross-reactive neutralizing antibodies through immortalized cell line selection.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.06.045
Abstract: Respiratory syncytial virus (RSV) is a significant cause of bronchiolitis and pneumonia. Protection against RSV is associated with neutralizing antibodies against the fusion (F) and attachment (G) glycoproteins. Several RSV vaccine candidates are in development,… read more here.
Keywords: immortalized cell; reactive neutralizing; rsv microneutralization; neutralizing antibodies ... See more keywords
A neuraminidase activity-based microneutralization assay for evaluating antibody responses to influenza H5 and H7 vaccines
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0207431
Abstract: Outbreaks of the highly pathogenic avian influenza H5N1 and H7N9 viruses have spurred an unprecedented research effort to develop antivirals and vaccines against influenza. Standardized methods for vaccine evaluation are critical for facilitating vaccine development.… read more here.
Keywords: influenza vaccines; activity; microneutralization assay; neuraminidase activity ... See more keywords
Microneutralization assay titer correlates analysis in two phase 3 trials of the CYD-TDV tetravalent dengue vaccine in Asia and Latin America
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0234236
Abstract: We previously showed that Month 13 50% plaque reduction neutralization test (PRNT50) neutralizing antibody (nAb) titers against dengue virus (DENV) correlated with vaccine efficacy (VE) of CYD-TDV against symptomatic, virologically-confirmed dengue (VCD) in the CYD14… read more here.
Keywords: cyd tdv; month; phase trials; microneutralization assay ... See more keywords
An Automated High-Throughput Enterovirus D68 Microneutralization Assay Platform.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of virological methods"
DOI: 10.2139/ssrn.4116434
Abstract: Virus neutralization assays, widely used to detect and quantify antibodies induced by virus infection, are considered the gold standard for enterovirus serology testing. Conventional microneutralization assays have been used to assess enterovirus D68 (EV-D68) seroprevalence.… read more here.
Keywords: microneutralization; serology; enterovirus d68; throughput ... See more keywords
Virus reduction neutralization test and LI-COR microneutralization assay bridging and WHO international standard calibration studies for respiratory syncytial virus.
Sign Up to like & getrecommendations! Published in 2022 at "Bioanalysis"
DOI: 10.4155/bio-2022-0097
Abstract: Background: Respiratory syncytial virus (RSV) vaccine is an unmet medical need. The virus reduction neutralization test (VRNT) was developed to replace the LI-COR microneutralization assay to measure RSV neutralization titers. Methods: A bridging study using selected… read more here.
Keywords: cor; calibration studies; neutralization; cor microneutralization ... See more keywords