A new imaging platform (iScreen) allows for the concurrent assessment of micronucleus induction and genotoxic mode of action in human A375 cells
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DOI: 10.1002/em.22496
Abstract: Genotoxicity testing guidelines require the assessment of the clastogenic and aneugenic potential of compounds. While in vitro micronucleus assays detect both types of endpoints, it requires labor‐intensive microscopic scoring and does not discriminate between the… read more here.
Keywords: imaging platform; platform; a375 cells; micronucleus induction ... See more keywords