Lipid-microparticles for pulmonary delivery of active pharmaceutical ingredients: impact of lipid crystallization on spray-drying processability.
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DOI: 10.1016/j.ijpharm.2021.121259
Abstract: Spray-drying is an extensively used technology for engineering inhalable particles. Important technical hurdles are however experienced when lipid-based excipients (LBEs) are spray-dried. Stickiness, extensive wall deposition, or simply inability to yield a solid product have… read more here.
Keywords: spray; spray drying; microparticles pulmonary; lipid crystallization ... See more keywords