Clinicopathological significance of microRNA‐21 in extracellular vesicles of pleural lavage fluid of lung adenocarcinoma and its functions inducing the mesothelial to mesenchymal transition
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.2928
Abstract: Pre‐resection pleural lavage cytology is useful to predict tumor recurrence and the prognosis of lung cancer patients. Recently, extracellular vesicles (EVs) isolated from effusion specimens have come under the spotlight, and several studies showed that… read more here.
Keywords: extracellular vesicles; mesothelial mesenchymal; lavage; pleural lavage ... See more keywords
The microRNA‐1908 up‐regulation in the peripheral blood cells impairs amyloid clearance by targeting ApoE
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.4881
Abstract: To give a new insight into the mechanism of ApoE dysregulation and microRNA‐1908 in Alzheimer's disease (AD). read more here.
Keywords: microrna 1908; peripheral blood; 1908 regulation; blood cells ... See more keywords
A strand displacement signal amplification-assisted fluorescence assay for sensitive detection of microRNA.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of separation science"
DOI: 10.1002/jssc.202300123
Abstract: MicroRNA is a vital biomarker because of its abnormal expression in the emergence and development of diseases, especially in cancers. Herein, a label-free fluorescent sensing platform is proposed for detecting microRNA-21, coupled with the cascade… read more here.
Keywords: signal amplification; amplification assisted; displacement signal; detection ... See more keywords
Functional high-throughput screening reveals miR-323a-5p and miR-342-5p as new tumor-suppressive microRNA for neuroblastoma
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03041-4
Abstract: Current therapies for most non-infectious diseases are directed at or affect functionality of the human translated genome, barely 2% of all genetic information. By contrast, the therapeutic potential of targeting the transcriptome, ~ 70% of the… read more here.
Keywords: 323a mir; mir 323a; mir 342; tumor suppressive ... See more keywords
Circulating microRNA-30a-5p, microRNA-101-3p, microRNA-140-3p and microRNA-141-3p as potential biomarkers for dexmedetomidine response in pediatric patients.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of clinical pharmacology"
DOI: 10.1007/s00228-021-03178-x
Abstract: PURPOSE The aim of this study was to investigate the expression levels of plasma miR-30a-5p, miR-101-3p, miR-140-3p and miR-141-3p and their relationship to dexmedetomidine efficacy and adverse effects in pediatric patients. METHODS The expression levels… read more here.
Keywords: mir 101; mir; 101 mir; mir 30a ... See more keywords
Functional annotation of differentially expressed fetal cardiac microRNA targets: implication for microRNA-based cardiovascular therapeutics
Sign Up to like & getrecommendations! Published in 2018 at "3 Biotech"
DOI: 10.1007/s13205-018-1520-8
Abstract: Gene expression pattern of a failing heart depicts remarkable similarity with developing fetal heart. Elucidating genetic as well as epigenetic mechanisms regulating the gene expression during cardiac development will improve our understanding of cardiovascular diseases.… read more here.
Keywords: functional annotation; fetal cardiac; differentially expressed; gene ... See more keywords
Label-free and sensitive microRNA detection based on a target recycling amplification-integrated superlong poly(thymine)-hosted copper nanoparticle strategy.
Sign Up to like & getrecommendations! Published in 2018 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2018.01.010
Abstract: Poly(thymine)-hosted copper nanoparticles (poly T-CuNPs) have emerged as a promising label-free fluorophore for bioanalysis, but its application in RNA-related studies is still rarely explored. Herein, by utilizing duplex-specific nuclease (DSN) as a convertor to integrate… read more here.
Keywords: detection; superlong poly; target; label free ... See more keywords
Post-synthesis functionalized hydrogel microparticles for high performance microRNA detection.
Sign Up to like & getrecommendations! Published in 2019 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2019.05.009
Abstract: Encoded hydrogel microparticles, synthesized by Stop Flow Lithography (SFL), have shown great potential for microRNA assays for their capability to provide high multiplexing capacity and solution-like hybridization kinetics. However, due to the low conversion of… read more here.
Keywords: synthesis; performance; hydrogel microparticles; microrna ... See more keywords
A combinatorial in silico approach for microRNA-target identification: Order out of chaos.
Sign Up to like & getrecommendations! Published in 2021 at "Biochimie"
DOI: 10.1016/j.biochi.2021.05.004
Abstract: Contemporary computational microRNA(miRNA)-target prediction tools have been playing a vital role in pursuing putative targets for a solitary miRNA or a group of miRNAs. These tools utilise a set of probabilistic algorithms, machine learning techniques… read more here.
Keywords: target identification; mirna target; microrna; target ... See more keywords
microRNAs and osteocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Bone"
DOI: 10.1016/j.bone.2021.115994
Abstract: microRNAs, identified in the early 1990s, are believed to regulate approximately 30% of the human genome. The role of microRNA in bone cells was first reported in 2007 in a manuscript showing that microRNA-223 is… read more here.
Keywords: micrornas osteocytes; microrna; biology; role ... See more keywords
Computational pathology aids derivation of microRNA biomarker signals from Cytosponge samples
Sign Up to like & getrecommendations! Published in 2022 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2022.103814
Abstract: Summary Background Non-endoscopic cell collection devices combined with biomarkers can detect Barrett's intestinal metaplasia and early oesophageal cancer. However, assays performed on multi-cellular samples lose information about the cell source of the biomarker signal. This… read more here.
Keywords: biomarker; microrna; computational pathology; pathology aids ... See more keywords