microRNA-124 targets glucocorticoid receptor and is involved in depression-like behaviors
Sign Up to like & getrecommendations! Published in 2017 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2017.07.024
Abstract: Dysregulation of microRNA (miRNA) has been shown to be involved in early observations of depression. MicroRNA-124-3p (miR-124) is the most abundant microRNA in the brain. Previous studies have shown that miR-124 plays a major role… read more here.
Keywords: depression; 124 targets; microrna 124; mir 124 ... See more keywords
Role of MicroRNA-124 as a Prognostic Factor in Multiple Neoplasms: A Meta-Analysis
Sign Up to like & getrecommendations! Published in 2019 at "Disease Markers"
DOI: 10.1155/2019/1654780
Abstract: Objective MicroRNA-124 (miR-124) was revealed to be an attractive prognostic tumour biomarker in recent studies. However, the results remain inconclusive. Hence, this meta-analysis was carried out to clarify the precise predictive value of miR-124. Materials… read more here.
Keywords: microrna 124; role; mir 124; survival ... See more keywords
MicroRNA-124 regulates the expression of MEKK3 in the inflammatory pathogenesis of Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-018-1053-4
Abstract: BackgroundParkinson’s disease (PD) is the most prevalent neurodegenerative disorder that is characterised by selective loss of midbrain dopaminergic (DA) neurons. Chronic inflammation of the central nervous system is mediated by microglial cells and plays a… read more here.
Keywords: mekk3; microrna 124; model; expression ... See more keywords
MicroRNA-124 inhibits proliferation and metastasis of esophageal cancer via negatively regulating NRP1.
Sign Up to like & getrecommendations! Published in 2021 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202103_25392
Abstract: This paper presents several inaccuracies and mistakes. Therefore, the article "MicroRNA-124 inhibits proliferation and metastasis of esophageal cancer via negatively regulating NRP1, by R.-K. Zang, J.-B. Ma, Y.-C. Liang, Y. Wang, S.-L. Hu, Y. Zhang,… read more here.
Keywords: inhibits proliferation; proliferation metastasis; esophageal cancer; metastasis esophageal ... See more keywords
MicroRNA-124 suppresses growth and aggressiveness of osteosarcoma and inhibits TGF-β-mediated AKT/GSK-3β/SNAIL-1 signaling.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular medicine reports"
DOI: 10.3892/mmr.2018.8637
Abstract: Osteosarcoma is one of the most common malignant tumors in adolescent populations and the prognosis remains incompletely understand. Previous reports have demonstrated that microRNA‑124 (miR‑124) has inhibitory effects on various human malignancies and is associated… read more here.
Keywords: microrna 124; osteosarcoma; 124 transfection; mir 124 ... See more keywords
Inhibition of microRNA‑124‑3p protects against acute myocardial infarction by suppressing the apoptosis of cardiomyocytes.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular medicine reports"
DOI: 10.3892/mmr.2019.10565
Abstract: The aims of the present study were to investigate the roles and underlying mechanisms of microRNA‑124‑3p (miR‑124‑3p) in the progression of acute myocardial infarction (AMI). The expression of miR‑124‑3p was determined via reverse transcription‑quantitative polymerase… read more here.
Keywords: h9c2 cells; microrna 124; expression; acute myocardial ... See more keywords
Comparison of MED 12 gene mutation and microRNA-124 expression in leiomyoma and myometrium of Turkish patients.
Sign Up to like & getrecommendations! Published in 2022 at "Ginekologia polska"
DOI: 10.5603/gp.a2021.0102
Abstract: OBJECTIVES It is believed that there are still unclear areas in the formation mechanism of leiomyomas. In our study, it was aimed to investigate the formation mechanisms of leiomyomas due to local MED 12 gene… read more here.
Keywords: expression; mutation; leiomyoma; microrna 124 ... See more keywords