Dysregulated circulating microRNA‐126 in chronic obstructive pulmonary disease: linkage with acute exacerbation risk, severity degree, and inflammatory cytokines
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24204
Abstract: MicroRNA‐126 (miR‐126) is engaged in respiratory diseases via regulating airway tissue injury and pulmonary inflammation, while its relation with chronic obstructive pulmonary disease (COPD) is not reported. The study aimed to evaluate the value of… read more here.
Keywords: microrna 126; disease; obstructive pulmonary; chronic obstructive ... See more keywords
Modulation of vascular endothelial cells under shear stress on electrospun membranes containing REDV and microRNA-126
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Polymeric Materials and Polymeric Biomaterials"
DOI: 10.1080/00914037.2020.1785452
Abstract: Abstract For blood vessel regeneration, rapid endothelialization is essential by the effective modulation of vascular endothelial cells (VECs). Herein, microRNA-126 was loaded in electrospun membranes of poly(ethylene glycol)-b-poly(L-lactide-co-ε-caprolactone) combined with REDV peptide to promote VEC… read more here.
Keywords: vascular endothelial; endothelial cells; modulation vascular; microrna 126 ... See more keywords
MicroRNA-126 Regulates Thrombosis Through Endothelial Progenitor Cells.
Sign Up to like & getrecommendations! Published in 2023 at "DNA and cell biology"
DOI: 10.1089/dna.2022.0643
Abstract: Thrombosis is a common problem with potentially severe consequences. Endothelial progenitor cells (EPCs) show great potential as a thrombosis therapy due to their angiogenesis-promoting, thrombus-relieving, and anticoagulant functions. However, cell therapies present more clinical challenges… read more here.
Keywords: microrna 126; 126 regulates; endothelial progenitor; regulates thrombosis ... See more keywords
Association of Gene Polymorphisms in the Human MicroRNA-126 Gene with Plasma-Circulating MicroRNA-126 Levels and Acute Myocardial Infarction.
Sign Up to like & getrecommendations! Published in 2019 at "Genetic testing and molecular biomarkers"
DOI: 10.1089/gtmb.2018.0282
Abstract: Objective: Our objective was to study the association of the human microRNA-126 (miR-126) gene rs4636297 and rs1140713 polymorphisms and the plasma-circulating miR-126 level in acute myocardial infarction (AMI). Methods: The genotypes of the miR-126 gene… read more here.
Keywords: rs4636297; mir 126; plasma circulating; 126 gene ... See more keywords
Letter by Gao and Shao Regarding Article, "MicroRNA-126-3p/-5p Overexpression Attenuates Blood-Brain Barrier Disruption in a Mouse Model of Middle Cerebral Artery Occlusion".
Sign Up to like & getrecommendations! Published in 2020 at "Stroke"
DOI: 10.1161/strokeaha.119.028846
Abstract: To the Editor: We read with great interest the recent study by Pan et al entitled “MicroRNA-126-3p/-5p Overexpression Attenuates Blood-Brain Barrier Disruption in a Mouse Model of Middle Cerebral Artery Occlusion” published in Stroke. The… read more here.
Keywords: brain barrier; adhesion; microrna 126; middle cerebral ... See more keywords
MicroRNA-126: Dual Role in Angiogenesis Dependent Diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Current pharmaceutical design"
DOI: 10.2174/1381612826666200504120737
Abstract: BACKGROUND MicroRNA-126, a microRNA implicated in blood vessel integrity and angiogenesis is significantly up/down regulated in different physiological and pathological conditions related to angiogenesis such as cardiovascular formation and angiogenesis dependent diseases like Cancer, diabetic… read more here.
Keywords: dependent diseases; angiogenesis; role angiogenesis; angiogenesis dependent ... See more keywords
The Effect of MicroRNA-126 Mimic Administration on Vascular Perfusion Recovery in an Animal Model of Hind Limb Ischemia
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.724465
Abstract: Background: MicroRNAs have been linked to angiogenesis and could prove to be valuable future therapeutic targets in ischemic cardiovascular diseases. Methods: Ten-week-old male C57Bl/6 mice were subjected to left femoral artery ligation and were treated… read more here.
Keywords: hind limb; day; group; microrna 126 ... See more keywords
A biomarker (MicroRNA-126) for diabetic retinopathy
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Ophthalmology"
DOI: 10.35841/clinical-ophthalmology.4.4.e003
Abstract: MiR-126 is a highly preserved, non-coding RNA that is expressed primarily in human endothelial cells and is a key regulator of angiogenesis and vasculogenesis. MiR-126 is found in human genomes within intron 7 of the… read more here.
Keywords: ophthalmology; microrna 126; mir 126; biomarker microrna ... See more keywords
Novel role of microRNA-126 in digestive system cancers: From bench to bedside
Sign Up to like & getrecommendations! Published in 2019 at "Oncology Letters"
DOI: 10.3892/ol.2018.9639
Abstract: MicroRNAs (miRNAs) are ubiquitously expressed, small, non-coding RNAs that regulate the expression of approximately 30% of the human genes at the post-transcriptional level. miRNAs have emerged as crucial modulators in the initiation and progression of… read more here.
Keywords: digestive system; mir 126; system cancers; role ... See more keywords