Downregulated microRNA‐150 upregulates IRX1 to depress proliferation, migration, and invasion, but boost apoptosis of gastric cancer cells
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DOI: 10.1002/iub.2214
Abstract: Many studies have reported the correlation of microRNAs (miRNAs) with cancers, yet few have proposed the function of miR‐150 in gastric cancer. This study intends to discuss the role of miR‐150 in gastric cancer development… read more here.
Keywords: microrna 150; upregulates irx1; gastric cancer; 150 upregulates ... See more keywords
MicroRNA-150 targets PU.1 and regulates macrophage differentiation and function in experimental autoimmune encephalomyelitis
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DOI: 10.1016/j.jneuroim.2018.06.010
Abstract: PU.1 is a transcription factor which is expressed in myeloid cells. Herein, we investigated the expression of PU.1 and its potentially targeting miRNAs in the central nervous system (CNS) of mice with experimental autoimmune encephalitis… read more here.
Keywords: autoimmune; microrna 150; targets regulates; mir 150 ... See more keywords
MicroRNA-150 and its target ETS-domain transcription factor 1 contribute to inflammation in diabetic photoreceptors.
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DOI: 10.1111/jcmm.17012
Abstract: Obesity-associated type 2 diabetes (T2D) is on the rise in the United States due to the obesity epidemic, and 60% of T2D patients develop diabetic retinopathy (DR) in their lifetime. Chronic inflammation is a hallmark… read more here.
Keywords: microrna 150; photoreceptor inflammation; inflammation; ets domain ... See more keywords
Macrophage microRNA-150 promotes pathological angiogenesis as seen in age-related macular degeneration.
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DOI: 10.1172/jci.insight.120157
Abstract: Macrophage aging is pathogenic in diseases of the elderly, including age-related macular degeneration (AMD), a leading cause of blindness in older adults. However, the role of microRNAs, which modulate immune processes, in regulating macrophage dysfunction… read more here.
Keywords: macular degeneration; microrna 150; age related; related macular ... See more keywords
Decreased MicroRNA-150 Exacerbates Neuronal Apoptosis in the Diabetic Retina
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DOI: 10.3390/biomedicines9091135
Abstract: Diabetic retinopathy (DR) is a chronic complication associated with diabetes and the number one cause of blindness in working adults in the US. More than 90% of diabetic patients have obesity-associated type 2 diabetes (T2D),… read more here.
Keywords: 150 exacerbates; microrna 150; apoptosis; decreased microrna ... See more keywords