microRNA‐186 alleviates oxygen‐glucose deprivation/reoxygenation‐induced injury by directly targeting hypoxia‐inducible factor‐1α
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DOI: 10.1002/jbt.22752
Abstract: Previous studies have suggested that microRNA‐186 (miR‐186) can be induced under hypoxic conditions, and is associated with apoptosis. This study was undertaken to explore the exact role of this microRNA (miRNA) in the apoptotic death… read more here.
Keywords: microrna 186; glucose deprivation; oxygen glucose; mir 186 ... See more keywords
Overexpression of microRNA‐186 inhibits angiogenesis in retinoblastoma via the Hedgehog signaling pathway by targeting ATAD2
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DOI: 10.1002/jcp.28545
Abstract: Retinoblastoma (RB) represents an aggressive malignancy in the eye during the period of infancy and childhood. We delineated the ability of microRNA‐186 (miR‐186) to influence viability, invasion, migration, angiogenesis, and apoptosis of RB via the… read more here.
Keywords: microrna 186; hedgehog signaling; angiogenesis; signaling pathway ... See more keywords
MicroRNA-186-5p Inhibits Proliferation And Metastasis Of Esophageal Cancer By Mediating HOXA9
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DOI: 10.2147/ott.s227920
Abstract: Objective MicroRNA (miRNA) is an endogenous, non-coding small RNA that plays a key role in regulating organism biology and pathology. The aim of this study was to investigate the expression characteristics of microRNA-186-5p in esophageal… read more here.
Keywords: expression; expression microrna; eca; proliferation ... See more keywords
Alteration of Pituitary Tumor Transforming Gene 1 by MicroRNA-186 and 655 Regulates Invasion Ability of Human Oral Squamous Cell Carcinoma
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DOI: 10.3390/ijms22031021
Abstract: Background: Pituitary tumor-transforming gene 1 (PTTG1) was recently shown to be involved in the progression as well as the metastasis of cancers. However, their expression and function in the invasion of oral squamous cell carcinoma… read more here.
Keywords: microrna 186; invasion; scc; 186 655 ... See more keywords
MicroRNA-186-3p attenuates tumorigenesis of cervical cancer by targeting MCM2
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DOI: 10.3892/ol.2021.12800
Abstract: The present study examined the effect of microRNA (miRNA/miR)-186-3p and its target gene, minichromosome maintenance complex component 2 (MCM2), on cervical cancer. Cervical cancer tissues and corresponding normal tissues were collected from 48 patients and… read more here.
Keywords: microrna 186; cervical cancer; expression; cancer ... See more keywords