Exosomes and MicroRNA‐223 at the Intersection of Inflammation and Fibrosis in NAFLD
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.31805
Abstract: Nonalcoholic fatty liver and nonalcoholic steatohepatitis (NASH) are the most common causes of liver disease. Progression of nonalcoholic fatty liver disease (NAFLD) to NASH is mediated by multiple signals that include activation of inflammatory cells,… read more here.
Keywords: inflammation fibrosis; intersection inflammation; exosomes microrna; fibrosis nafld ... See more keywords
MicroRNA-223 Suppresses Human Hepatic Stellate Cell Activation Partly via Regulating the Actin Cytoskeleton and Alleviates Fibrosis in Organoid Models of Liver Injury
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23169380
Abstract: MicroRNAs (miRNAs) are small, non-coding RNAs that negatively regulate target mRNA expression, and altered expression of miRNAs is associated with liver pathological conditions. Recent studies in animal models have shown neutrophil/myeloid-specific microRNA-223 (miR-223) as a… read more here.
Keywords: hscs; organoid models; microrna 223; mir 223 ... See more keywords