H2O2 down-regulates SIRT7’s protective role of endothelial premature dysfunction via microRNA-335-5p
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DOI: 10.1042/bsr20211775
Abstract: Abstract Endothelial senescence is believed to constitute the initial pathogenesis of the atherosclerotic cardiovascular disease (ASCVD). MicroRNA-335-5p (miR-335-5p) expression is significantly up-regulated in oxidative stress-induced endothelial cells (ECs). Sirtuin7 (SIRT7) is considered to prevent EC… read more here.
Keywords: mir 335; microrna 335; sirt7; senescence ... See more keywords