THU0050 Microrna-365 inhibits il-1β-induced catabolic factor expression by targeting hif-2α in human primary chondrocytes
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DOI: 10.1136/annrheumdis-2017-eular.2818
Abstract: Background MicroRNAs, small noncoding RNA molecules, are involved in the pathogenesis of various diseases such as cancer and arthritis. Endothelial PAS domain protein-1/hypoxia-inducible factor-2α (EPAS-1/ HIF-2α) is a catabolic transcription factor that regulates osteoarthritis (OA)… read more here.
Keywords: hif; microrna 365; expression; factor ... See more keywords