MicroRNA‐494 regulates high glucose‐induced cardiomyocyte apoptosis and autophagy by PI3K/AKT/mTOR signalling pathway
Sign Up to like & getrecommendations! Published in 2023 at "ESC Heart Failure"
DOI: 10.1002/ehf2.14311
Abstract: Diabetic cardiomyopathy (DCM) is one of the major cardiovascular complications of diabetes. However, the mechanism of DCM is not fully understood. Studies have confirmed that certain microRNAs (miRNAs/miRs) are key regulators of DCM. The aim… read more here.
Keywords: microrna 494; high glucose; cardiomyocyte apoptosis; apoptosis autophagy ... See more keywords
Silencing of microRNA‐494 inhibits the neurotoxic Th1 shift via regulating HDAC2‐STAT4 cascade in ischaemic stroke
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DOI: 10.1111/bph.14852
Abstract: T helper cell 1 (Th1)‐skewed neurotoxicity contributes to the poor outcome of stroke in rodents. Here, we have elucidated the mechanism of the Th1/Th2 shift in acute ischaemic stroke (AIS) patients at hyperacute phase and… read more here.
Keywords: shift; 494 inhibits; ischaemic stroke; silencing microrna ... See more keywords
microRNA-494 and ATF3 the targets of onconase(?)
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DOI: 10.18632/oncotarget.13799
Abstract: Onconase (Onc; also named ranpirnase), a 12 kD ribonuclease from oocytes of northern leopard frogs (Rana pipiens), is cytostatic and cytotoxic to variety tumor cell lines, inhibits growth of tumors in model animals and advanced… read more here.
Keywords: 494 atf3; cell lines; atf3 targets; targets onconase ... See more keywords