MicroRNA detection at femtomolar concentrations with isothermal amplification and a biological nanopore.
Sign Up to like & getrecommendations! Published in 2017 at "Nanoscale"
DOI: 10.1039/c7nr04215a
Abstract: One of the greatest challenges faced by chemists and biologists is the detection of molecules at extremely low concentrations. This paper describes a method to detect ultra-low concentrations (1 femtomole) of nucleotides using isothermal amplification… read more here.
Keywords: amplification biological; biological nanopore; isothermal amplification; detection femtomolar ... See more keywords
An entropy-driven DNA nanomachine for microRNA detection using a personal glucose meter.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc06479k
Abstract: Herein, we developed a reliable and portable biosensor (TDR-PGM nanomachine) for the sensitive detection of microRNA by integrating an efficient toehold-mediated strand displacement reaction module (TDR) and a personal glucose meter (PGM). The system provides… read more here.
Keywords: personal glucose; detection; glucose meter; microrna detection ... See more keywords
Spectrophotometric and Electrochemical Determination of MicroRNA-155 Using Sandwich Hybridization Magnetic Beads
Sign Up to like & getrecommendations! Published in 2018 at "Analytical Letters"
DOI: 10.1080/00032719.2017.1302460
Abstract: ABSTRACT Here a new colorimetric assay and electrochemical biosensor for microRNA detection based on magnetic bead separation and enzyme amplification are reported. MicroRNA-155 was selected as a model because of its involvement in breast and… read more here.
Keywords: detection; microrna 155; spectrophotometric electrochemical; magnetic beads ... See more keywords
DNA nanotechnology approaches for microRNA detection and diagnosis
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz580
Abstract: Abstract MicroRNAs are involved in the crucial processes of development and diseases and have emerged as a new class of biomarkers. The field of DNA nanotechnology has shown great promise in the creation of novel… read more here.
Keywords: dna; nanotechnology approaches; microrna detection; nanotechnology ... See more keywords
microRNA Detection via Nanostructured Biochips for Early Cancer Diagnostics
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24097762
Abstract: MicroRNA (miRNA) are constituted of approximately 22 nucleotides and play an important role in the regulation of many physiological functions and diseases. In the last 10 years, an increasing interest has been recorded in studying… read more here.
Keywords: microrna detection; detection via; detection; nanostructured biosensors ... See more keywords