Regulation of microRNA‐21 expression by natural products in cancer
Sign Up to like & getrecommendations! Published in 2021 at "Phytotherapy Research"
DOI: 10.1002/ptr.7069
Abstract: Natural products have been of much interest in research studies owing to their wide pharmacological applications, chemical diversity, low side effects, and multitarget activities. Examples of these compounds include matrine, sulforaphane, silibinin, curcumin, berberin, resveratrol,… read more here.
Keywords: regulation microrna; microrna expression; natural products; expression ... See more keywords
MicroRNA Expression in Multistage Date Fruit Development.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7159-6_25
Abstract: MicroRNAs (miRNAs) are small endogenous noncoding RNAs. Plant miRNAs are known to play important regulatory roles in homeostasis, stress response, and diverse developmental processes. Here, we describe the identification of conserved miRNAs in date palm… read more here.
Keywords: microrna expression; date; fruit development; multistage ... See more keywords
MicroRNA Expression Analysis Using Small RNA Sequencing Discovery and RT-qPCR-Based Validation.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7231-9_13
Abstract: miRNAs are small noncoding RNA molecules that function as regulators of gene expression. Deregulated miRNA expression has been reported in various diseases including cancer. Due to their small size and high degree of homology, accurate… read more here.
Keywords: small rna; microrna expression; rna sequencing; expression ... See more keywords
Centenarian offspring: A model for understanding healthy aging
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.257
Abstract: Centenarians exhibit extreme longevity showing a compression of morbidity. We showed previously that microRNA expression profiles and plasma protein carbonylation in centenarians and young people are similar, whereas they are very different from that found… read more here.
Keywords: protein carbonylation; centenarian offspring; healthy aging; microrna expression ... See more keywords
Evidence for a potential role of miR-1908-5p and miR-3614-5p in autoimmune disease risk using integrative bioinformatics.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2018.07.010
Abstract: Genome-wide association studies (GWAS) have identified a large number of genetic risk loci for autoimmune diseases. However, the functional variants underlying these disease associations remain largely unknown. There is evidence that microRNA-mediated regulation may play… read more here.
Keywords: microrna expression; risk; mir; disease ... See more keywords
MicroRNA expression patterns in the brown fat of hibernating 13-lined ground squirrels.
Sign Up to like & getrecommendations! Published in 2021 at "Genomics"
DOI: 10.1016/j.ygeno.2021.01.017
Abstract: The sequence diversity of microRNAs (miRNAs) allows these potent regulators of mRNA fate to bind multiple transcripts, giving them the power to inhibit diverse cellular processes. Therefore, miRNAs may regulate metabolic rate suppression (also termed… read more here.
Keywords: microrna expression; ground squirrels; expression patterns; patterns brown ... See more keywords
Oct4-mediated reprogramming induces embryonic-like microRNA expression signatures in human fibroblasts
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-52294-3
Abstract: Oct4-mediated reprogramming has recently become a novel tool for the generation of various cell types from differentiated somatic cells. Although molecular mechanisms underlying this process are unknown, it is well documented that cells over-expressing Oct4… read more here.
Keywords: state; microrna expression; oct4 mediated; human fibroblasts ... See more keywords
Identification and validation of microRNAs that synergize with miR-34a – a basis for combinatorial microRNA therapeutics
Sign Up to like & getrecommendations! Published in 2019 at "Cell Cycle"
DOI: 10.1080/15384101.2019.1634956
Abstract: ABSTRACT Efforts to search for better treatment options for cancer have been a priority, and due to these efforts, new alternative therapies have emerged. For instance, clinically relevant tumor-suppressive microRNAs that target key oncogenic drivers… read more here.
Keywords: cancer; mir 34a; combinatorial microrna; microrna expression ... See more keywords
CMEP: a database for circulating microRNA expression profiling
Sign Up to like & getrecommendations! Published in 2019 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btz042
Abstract: Motivation In recent years, several experimental studies have revealed that the microRNAs (miRNAs) in serum, plasma, exosome, and whole blood are dysregulated in various types of diseases, indicating that the circulating miRNAs may serve as… read more here.
Keywords: microrna expression; circulating microrna; expression; database ... See more keywords
isomiRdb: microRNA expression at isoform resolution
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac884
Abstract: Abstract A significant fraction of mature miRNA transcripts carries sequence and/or length variations, termed isomiRs. IsomiRs are differentially abundant in cell types, tissues, body fluids or patients’ samples. Not surprisingly, multiple studies describe a physiological… read more here.
Keywords: isoform; microrna expression; expression; isomirdb microrna ... See more keywords
Age‐associated microRNA expression in human peripheral blood is associated with all‐cause mortality and age‐related traits
Sign Up to like & getrecommendations! Published in 2018 at "Aging Cell"
DOI: 10.1111/acel.12687
Abstract: Recent studies provide evidence of correlations of DNA methylation and expression of protein‐coding genes with human aging. The relations of microRNA expression with age and age‐related clinical outcomes have not been characterized thoroughly. We explored… read more here.
Keywords: microrna expression; age related; age; blood ... See more keywords