The microRNA-7-mediated reduction in EPAC-1 contributes to vascular endothelial permeability and eNOS uncoupling in murine experimental retinopathy
Sign Up to like & getrecommendations! Published in 2017 at "Acta Diabetologica"
DOI: 10.1007/s00592-017-0985-y
Abstract: AbstractAims To investigate the consequences of oxidative stress and hypoxia on EPAC-1 expression during retinopathy.MethodsOxygen-induced retinopathy was induced in mice and EPAC-1 expression investigated by immunofluorescence. In silico analyses were used to identify a link… read more here.
Keywords: endothelial permeability; epac expression; expression; epac ... See more keywords
MicroRNA-Mediated Dynamic Bidirectional Shift between the Subclasses of Glioblastoma Stem-like Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.05.040
Abstract: Large-scale transcriptomic profiling of glioblastoma (GBM) into subtypes has provided remarkable insight into the pathobiology and heterogeneous nature of this disease. The mechanisms of speciation and inter-subtype transitions of these molecular subtypes require better characterization to… read more here.
Keywords: like cells; stem like; mediated dynamic; glioblastoma stem ... See more keywords
microRNA-mediated noise processing in cells: A fight or a game?
Sign Up to like & getrecommendations! Published in 2020 at "Computational and Structural Biotechnology Journal"
DOI: 10.1016/j.csbj.2020.02.020
Abstract: In the past decades, microRNAs (miRNA) have much attracted the attention of researchers at the interface between life and theoretical sciences for their involvement in post-transcriptional regulation and related diseases. Thanks to the always more… read more here.
Keywords: processing cells; noise processing; cells fight; mediated noise ... See more keywords
MicroRNA-mediated control of myocardial infarction in diabetes.
Sign Up to like & getrecommendations! Published in 2022 at "Trends in cardiovascular medicine"
DOI: 10.1016/j.tcm.2022.01.004
Abstract: Diabetes mellitus is a global public health problem whose cases will continue to rise along with the progressive increase in obesity and the aging of the population. People with diabetes exhibit higher risk of cardiovascular… read more here.
Keywords: infarction; myocardial infarction; control myocardial; microrna mediated ... See more keywords
MicroRNA-mediated regulation of agronomically important seed traits: a treasure trove with shades of grey!
Sign Up to like & getrecommendations! Published in 2021 at "Critical Reviews in Biotechnology"
DOI: 10.1080/07388551.2021.1873238
Abstract: Abstract Seed development is an intricate process with multiple levels of regulation. MicroRNAs (miRNAs) have emerged as one of the crucial components of molecular networks underlying agronomically important seed traits in diverse plant species. In… read more here.
Keywords: seed; microrna mediated; seed traits; important seed ... See more keywords
Mechanistic Insights into MicroRNA-Mediated Gene Silencing.
Sign Up to like & getrecommendations! Published in 2019 at "Cold Spring Harbor perspectives in biology"
DOI: 10.1101/cshperspect.a032771
Abstract: MicroRNAs (miRNAs) posttranscriptionally regulate gene expression by repressing protein synthesis and exert a broad influence over development, physiology, adaptation, and disease. Over the past two decades, great strides have been made toward elucidating how miRNAs… read more here.
Keywords: mediated gene; gene silencing; gene; insights microrna ... See more keywords
MicroRNA‐mediated regulation of immune responses to intestinal helminth infections
Sign Up to like & getrecommendations! Published in 2017 at "Parasite Immunology"
DOI: 10.1111/pim.12406
Abstract: Intestinal helminth infections are highly prevalent in the developing world, often resulting in chronic infection and inflicting high host morbidity. With the emergence of drug‐resistant parasites, a limited number of chemotherapeutic drugs available and stalling… read more here.
Keywords: mediated regulation; immune responses; intestinal helminth; helminth infections ... See more keywords
microRNA-Mediated Encoding and Decoding of Time-Dependent Signals in Tumorigenesis
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12020213
Abstract: microRNAs, pivotal post-transcriptional regulators of gene expression, in the past decades have caught the attention of researchers for their involvement in different biological processes, ranging from cell development to cancer. Although lots of effort has… read more here.
Keywords: tumorigenesis; time dependent; encoding decoding; microrna mediated ... See more keywords
MicroRNA-Mediated Gene Regulatory Mechanisms in Mammalian Female Reproductive Health
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22020938
Abstract: Mammalian reproductive health affects the entire reproductive cycle starting with the ovarian function through implantation and fetal growth. Various environmental and physiological factors contribute to disturbed reproductive health status leading to infertility problems in mammalian… read more here.
Keywords: mediated gene; gene regulatory; regulatory mechanisms; reproductive health ... See more keywords
microRNA-mediated regulation of microRNA machinery controls cell fate decisions
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.72289
Abstract: microRNAs associate with Argonaute proteins, forming the microRNA-induced silencing complex (miRISC), to repress target gene expression post-transcriptionally. Although microRNAs are critical regulators in mammalian cell differentiation, our understanding of how microRNA machinery, such as the… read more here.
Keywords: regulation microrna; mediated regulation; microrna machinery; microrna mediated ... See more keywords