MicroRNA miR-21 Decreases Post-stroke Brain Damage in Rodents.
Sign Up to like & getrecommendations! Published in 2021 at "Translational stroke research"
DOI: 10.1007/s12975-021-00952-y
Abstract: Due to their role in controlling translation, microRNAs emerged as novel therapeutic targets to modulate post-stroke outcomes. We previously reported that miR-21 is the most abundantly induced microRNA in the brain of rodents subjected to… read more here.
Keywords: post stroke; microrna mir; mir mimic; brain ... See more keywords
The microRNA miR‐184 regulates the CYP303A1 transcript level to control molting of Locusta migratoria
Sign Up to like & getrecommendations! Published in 2020 at "Insect Science"
DOI: 10.1111/1744-7917.12837
Abstract: Cytochrome P450 monooxygenases (CYPs) play essential physiological functions in insects. CYP303A1 is highly conserved in insect species studied to date, and shows an indispensable role for adult eclosion in both Locusta migratoria and Drosophila melanogaster.… read more here.
Keywords: control; mir 184; microrna mir; locusta migratoria ... See more keywords
Interferon-Inducible MicroRNA miR-128 Modulates HIV-1 Replication by Targeting TNPO3 mRNA
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Virology"
DOI: 10.1128/jvi.00364-19
Abstract: HIV-1 is the causative agent of AIDS. During HIV-1 infection, type I interferons (IFNs) are induced, and their effectors limit HIV-1 replication at multiple steps in its life cycle. However, the cellular targets of INFs… read more here.
Keywords: hiv replication; microrna mir; mir 128; replication ... See more keywords
MicroRNA miR-34a-5p inhibition restrains oxidative stress injury of macrophages by targeting MDM4
Sign Up to like & getrecommendations! Published in 2022 at "Vascular"
DOI: 10.1177/17085381211069447
Abstract: Objective Atherosclerosis is a chronic cardiovascular disease associated with oxidative stress damage, which is caused by excessive oxidation of low-density lipoprotein (ox-LDL). The role of microRNA miR-34a-5p on oxidative stress in ox-LDL–treated macrophages was investigated… read more here.
Keywords: mdm4; stress injury; oxidative stress; microrna mir ... See more keywords
MicroRNA miR-301a is a novel cardiac regulator of Cofilin-2
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0183901
Abstract: Calsarcin-1 deficient mice develop dilated cardiomyopathy (DCM) phenotype in pure C57BL/6 genetic background (Cs1-ko) despite severe contractile dysfunction and robust activation of fetal gene program. Here we performed a microRNA microarray to identify the molecular… read more here.
Keywords: mir 301a; cs1 mice; microrna mir; cfl2 ... See more keywords
Potential role for microRNA-16 (miR-16) and microRNA-93 (miR-93) in diagnosis and prediction of disease progression in mycosis fungoides in Egyptian patients
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0224305
Abstract: Mycosis Fungoides (MF) is the most common type of cutaneous T-cell lymphomas. Early stage patients are treated with topical therapies and have normal life expectancy whereas patients with advanced disease encounter frequent relapses and have… read more here.
Keywords: mycosis fungoides; expression; mir microrna; microrna mir ... See more keywords
The microRNA miR-10b as a potentially promising biomarker to predict the prognosis of cancer patients: a meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.21428
Abstract: Background Reported studies on carcinoma have evaluated the significance of the microRNA miR-10b in the development and progression of many cancers. Increased expression of miR-10b is associated with the susceptibility to lymph node metastasis and… read more here.
Keywords: analysis; mir 10b; metastasis; expression ... See more keywords
MicroRNA miR-722 Inhibits Cyprinid Herpesvirus 3 Replication via Targeting the Viral Immune Evasion Protein ORF89, Which Negatively Regulates IFN by Degrading IRF3.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of immunology"
DOI: 10.4049/jimmunol.2200025
Abstract: Cyprinid herpesvirus 3 (CyHV-3) has caused severe economic losses to carp culture, but its pathogenicity is far from clear. Our previous study has revealed that microRNA (miR)-722 was upregulated during CyHV-3 infection, indicating that miR-722… read more here.
Keywords: mir 722; replication; ifn; microrna mir ... See more keywords
Replication Study: The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.43511
Abstract: As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Li et al., 2015), that described how we intended to replicate selected experiments from the paper ‘The microRNA miR-34a inhibits prostate cancer… read more here.
Keywords: mir 34a; study; microrna mir; prostate cancer ... See more keywords