Identification of key genes and construction of microRNA–mRNA regulatory networks in multiple myeloma by integrated multiple GEO datasets using bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Hematology"
DOI: 10.1007/s12185-017-2216-2
Abstract: Multiple myeloma (MM) is a common hematological malignancy. To identify key genes and microRNAs in MM, we downloaded two gene expression profiles (GSE16558 and GSE47552) and two microRNA expression profiles (GSE17498 and GSE16558) from the… read more here.
Keywords: multiple myeloma; key genes; signaling pathway; microrna mrna ... See more keywords
Integrated microRNA/mRNA expression profiling of the skin of psoriasis patients.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2019.11.003
Abstract: BACKGROUND Psoriasis is a chronic inflammatory disease characterized by demarcated, raised, and scaling skin lesions. It often serves as a model for immune-mediated disorders. Gene expression profiling of affected skin has allowed insights into psoriasis… read more here.
Keywords: expression profiling; expression; microrna mrna; psoriasis ... See more keywords
An integrated analysis revealed different microRNA-mRNA profiles during skeletal muscle development between Landrace and Lantang pigs
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-02558-7
Abstract: Pigs supply vital dietary proteins for human consumption, and their economic value depends largely on muscle production. MicroRNAs are known to play important roles in skeletal muscle development. However, their relationship to distinct muscle production… read more here.
Keywords: skeletal muscle; muscle; analysis; muscle development ... See more keywords
Integrated analysis of microRNA and mRNA expression profiles in splenomegaly induced by non-cirrhotic portal hypertension in rats
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-36297-0
Abstract: The spleen plays an important role in the immune and hematopoietic systems. Splenomegaly is a frequent consequence of portal hypertension, but the underlying molecular and cellular mechanisms remain to be fully elucidated. In this study,… read more here.
Keywords: analysis; expression; microrna mrna; hypertension ... See more keywords
Genome-wide integrative analysis of circular RNA dysregulation and the corresponding circular RNA-microRNA-mRNA regulatory axes in autism.
Sign Up to like & getrecommendations! Published in 2020 at "Genome research"
DOI: 10.1101/gr.255463.119
Abstract: Circular RNAs (circRNAs), a class of long noncoding RNAs, are known to be enriched in mammalian neural tissues. While a wide range of dysregulation of gene expression in autism spectrum disorder (ASD) have been reported,… read more here.
Keywords: circular rna; asd; dysregulation; microrna mrna ... See more keywords
Identification of potential crucial genes and construction of microRNA-mRNA negative regulatory networks in osteosarcoma
Sign Up to like & getrecommendations! Published in 2018 at "Hereditas"
DOI: 10.1186/s41065-018-0061-9
Abstract: BackgroundThis study aimed to identify potential crucial genes and construction of microRNA-mRNA negative regulatory networks in osteosarcoma by comprehensive bioinformatics analysis.MethodsData of gene expression profiles (GSE28424) and miRNA expression profiles (GSE28423) were downloaded from GEO… read more here.
Keywords: network; mrna negative; microrna mrna; negative regulatory ... See more keywords
Identification of MicroRNA–mRNA Networks in Melanoma and Their Association with PD-1 Checkpoint Blockade Outcomes
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13215301
Abstract: Simple Summary We conducted a network analysis of microRNA–mRNA associations in melanoma tissue and cell lines to identify the microRNAs central to melanoma biology and their associated gene expression profiles. Further, we evaluated expression of… read more here.
Keywords: melanoma; networks melanoma; mrna networks; expression ... See more keywords
MicroRNA and mRNA Expression Changes in Glioblastoma Cells Cultivated under Conditions of Neurosphere Formation
Sign Up to like & getrecommendations! Published in 2022 at "Current Issues in Molecular Biology"
DOI: 10.3390/cimb44110360
Abstract: Glioblastoma multiforme (GBM) is one of the most highly metastatic cancers. The study of the pathogenesis of GBM, as well as the development of targeted oncolytic drugs, require the use of actual cell models, in… read more here.
Keywords: microrna mrna; mrna expression; hsa mir; gbm ... See more keywords
Transcriptome-Wide Analysis of microRNA–mRNA Correlations in Tissue Identifies microRNA Targeting Determinants
Sign Up to like & getrecommendations! Published in 2023 at "Non-Coding RNA"
DOI: 10.3390/ncrna9010015
Abstract: MicroRNAs are small RNAs that regulate gene expression through complementary base pairing with their target mRNAs. A substantial understanding of microRNA target recognition and repression mechanisms has been reached using diverse empirical and bioinformatic approaches,… read more here.
Keywords: mer; microrna mrna; transcriptome wide; wide analysis ... See more keywords
MicroRNA and mRNA Dysregulation in Astrocytes Infected with Zika Virus
Sign Up to like & getrecommendations! Published in 2017 at "Viruses"
DOI: 10.3390/v9100297
Abstract: The Zika virus (ZIKV) epidemic is an ongoing public health concern. ZIKV is a flavivirus reported to be associated with microcephaly, and recent work in animal models demonstrates the ability of the virus to cross… read more here.
Keywords: mrna dysregulation; dysregulation astrocytes; microrna mrna; astrocytes infected ... See more keywords