Issues in current microRNA target identification methods
Sign Up to like & getrecommendations! Published in 2017 at "RNA Biology"
DOI: 10.1080/15476286.2017.1320469
Abstract: ABSTRACT microRNAs are currently believed to control a large diversity of physiologic processes, through the collective repression of thousands of target genes. Both experimental and computational analyses indeed suggest that each microRNA regulates tens or… read more here.
Keywords: target identification; issues current; microrna target; current microrna ... See more keywords
MIO: microRNA target analysis system for immuno-oncology
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac366
Abstract: Abstract Summary MicroRNAs have been shown to be able to modulate the tumor microenvironment and the immune response and hence could be interesting biomarkers and therapeutic targets in immuno-oncology; however, dedicated analysis tools are missing.… read more here.
Keywords: oncology; microrna target; mio; analysis ... See more keywords
The Impact of Population Variation in the Analysis of microRNA Target Sites
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DOI: 10.3390/ncrna5020042
Abstract: The impact of population variation in the analysis of regulatory interactions is an underdeveloped area. MicroRNA target recognition occurs via pairwise complementarity. Consequently, a number of computational prediction tools have been developed to identify potential… read more here.
Keywords: variation; target sites; target; microrna target ... See more keywords