MicroRNAs: Biomarkers, Diagnostics, and Therapeutics.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7046-9_4
Abstract: MicroRNAs (miRNAs) are small noncoding RNAs (21-23 nucleotides in length) that regulate gene expression at translational or posttranslational levels. The major regulatory mechanisms include translational repression or mRNA degradation (Filipowicz et al., Curr Opin Struct… read more here.
Keywords: micrornas biomarkers; medicine; biomarkers diagnostics; expression ... See more keywords
MicroRNAs as biomarkers and perspectives in the therapy of pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-021-04233-y
Abstract: Pancreatic cancer is considered as one of the most aggressive tumor types, representing over 45,750 mortality cases annually in the USA solely. The aggressive nature and late identification of pancreatic cancer, combined with the restrictions… read more here.
Keywords: therapy pancreatic; micrornas biomarkers; biomarkers perspectives; pancreatic cancer ... See more keywords
Factors influencing circulating microRNAs as biomarkers for liver diseases.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular biology reports"
DOI: 10.1007/s11033-022-07170-1
Abstract: MicroRNAs (microRNAs) have been implicated to play crucial roles in various liver diseases. Hepatic microRNAs are released in to the circulation in a systematic fashion, and are, therefore, being extensively explored for their role as… read more here.
Keywords: liver diseases; biomarkers liver; micrornas biomarkers; factors influencing ... See more keywords
Role of microRNAs As Biomarkers in Sepsis-Associated Encephalopathy
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Neurobiology"
DOI: 10.1007/s12035-021-02445-3
Abstract: Sepsis-associated encephalopathy (SAE) is a neurological complication of sepsis, characterized by brain dysfunction without any direct central nervous system infection. The diagnosis of SAE is currently a challenge. In fact, problems in making a diagnosis… read more here.
Keywords: micrornas biomarkers; diagnosis; associated encephalopathy; sepsis associated ... See more keywords
Identification of microRNAs as biomarkers for cholangiocarcinoma detection: A diagnostic meta-analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2016.10.007
Abstract: BACKGROUND Cholangiocarcinoma (CCA) is a common biliary malignancy that results in high mortality and poor survival rates. The diagnostic capacity of miRNAs in CCA detection is still controversial. Current meta-analysis evaluate the evidence on the… read more here.
Keywords: micrornas biomarkers; detection; analysis; identification micrornas ... See more keywords
Potential of MicroRNAs As Biomarkers and Therapeutic Targets in Respiratory Viruses: A Literature Review.
Sign Up to like & getrecommendations! Published in 2022 at "DNA and cell biology"
DOI: 10.1089/dna.2021.1101
Abstract: MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression through recognition of cognate sequences and interference of transcriptional, translational, or epigenetic processes. Hundreds of miRNA genes have been found in diverse viruses, and many… read more here.
Keywords: micrornas biomarkers; potential micrornas; respiratory viruses; targets respiratory ... See more keywords
Diagnostic Potential of MicroRNAs as Biomarkers in the Detection of Preeclampsia.
Sign Up to like & getrecommendations! Published in 2020 at "Genetic testing and molecular biomarkers"
DOI: 10.1089/gtmb.2019.0264
Abstract: Preeclampsia is a multisystemic disorder that occurs in 5-8% of pregnant women and remains a leading cause of both maternal and fetal morbidity and mortality. The disease is characterized by the abnormal vascular response to… read more here.
Keywords: diagnostic potential; micrornas biomarkers; detection preeclampsia; biomarkers detection ... See more keywords
MicroRNAs as Biomarkers in Thyroid Carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Genomics"
DOI: 10.1155/2017/6496570
Abstract: Optimal management of patients with thyroid cancer requires the use of sensitive and specific biomarkers. For early diagnosis and effective follow-up, the currently available cytological and serum biomarkers, thyroglobulin and calcitonin, present severe limitations. Research… read more here.
Keywords: micrornas biomarkers; biomarkers thyroid; thyroid carcinoma;
Circulating MicroRNAs as Biomarkers of Gestational Diabetes Mellitus: Updates and Perspectives
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Endocrinology"
DOI: 10.1155/2018/6380463
Abstract: Gestational diabetes mellitus (GDM) is defined as any degree of carbohydrate intolerance, with onset or first recognition during second or third trimester of gestation. It is estimated that approximately 7% of all pregnancies are complicated… read more here.
Keywords: gestational diabetes; micrornas biomarkers; mellitus updates; diabetes mellitus ... See more keywords
Corrigendum: An Overview of MicroRNAs as Biomarkers of ALS
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2019.01129
Abstract: [This corrects the article DOI: 10.3389/fneur.2019.00186.]. read more here.
Keywords: micrornas biomarkers; biomarkers als; corrigendum overview; overview micrornas ... See more keywords
The potential function of microRNAs as biomarkers and therapeutic targets in multiple myeloma
Sign Up to like & getrecommendations! Published in 2018 at "Oncology Letters"
DOI: 10.3892/ol.2018.8157
Abstract: Multiple myeloma (MM), accounting for ~1% of all types of human cancer and 13% of all hematological malignancies, is characterized by the malignant proliferation of monoclonal plasma cells (PCs) in the bone marrow. MM leads… read more here.
Keywords: micrornas biomarkers; therapeutic targets; multiple myeloma; potential function ... See more keywords