Role of microRNAs in doxorubicin-induced cardiotoxicity: an overview of preclinical models and cancer patients
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DOI: 10.1007/s10741-017-9653-0
Abstract: Cardiotoxicity is a well-known side effect of doxorubicin (DOX), but the mechanisms leading to this phenomenon are still not completely clear. Prediction of drug-induced dysfunction onset is difficult and is still largely based on detection… read more here.
Keywords: dox induced; induced cardiotoxicity; micrornas doxorubicin; cardiotoxicity ... See more keywords
MicroRNAs in doxorubicin-induced cardiotoxicity: The DNA damage response
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DOI: 10.3389/fphar.2022.1055911
Abstract: Doxorubicin (DOX) is a chemotherapeutic drug widely used for cancer treatment, but its use is limited by cardiotoxicity. Although free radicals from redox cycling and free cellular iron have been predominant as the suggested primary… read more here.
Keywords: induced cardiotoxicity; micrornas doxorubicin; dna damage; cardiotoxicity ... See more keywords