Articles with "microsampling vams" as a keyword



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Volumetric absorptive microsampling (VAMS) as an alternative to conventional dried blood spots in the quantification of miltefosine in dried blood samples

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Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"

DOI: 10.1016/j.jpba.2016.12.012

Abstract: &NA; Miltefosine is an oral agent against the neglected tropical disease leishmaniasis, which is mostly endemic in resource‐poor areas. Dried blood spot (DBS) sampling is an attractive alternative to plasma sampling for pharmacokinetic studies in… read more here.

Keywords: microsampling vams; absorptive microsampling; blood spot; dried blood ... See more keywords
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Volumetric absorptive microsampling (VAMS) for the quantification of ten kinase inhibitors and determination of their in vitro VAMS-to-plasma ratio.

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Published in 2022 at "Journal of pharmaceutical and biomedical analysis"

DOI: 10.1016/j.jpba.2022.114623

Abstract: Personalized dosing of kinase inhibitors (KI) might be beneficial in oral anti-cancer therapy to overcome individual pharmacokinetic variability. Volumetric absorptive microsampling (VAMS) has emerged as an attractive alternative compared to conventional invasive sampling methods enabling… read more here.

Keywords: volumetric absorptive; absorptive microsampling; microsampling vams; kinase inhibitors ... See more keywords
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Volumetric Absorptive Microsampling (VAMS) for Targeted LC-MS/MS Determination of Tryptophan-Related Biomarkers

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules27175652

Abstract: L-Tryptophan (TRP) metabolites and related biomarkers play crucial roles in physiological functions, and their imbalances are implicated in central nervous system pathologies and neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer’s disease, Parkinson’s disease,… read more here.

Keywords: related biomarkers; volumetric absorptive; microsampling vams; determination ... See more keywords