Articles with "microscale" as a keyword



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Microscale disruption of microorganisms for parallelized process development

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Published in 2017 at "Biotechnology Journal"

DOI: 10.1002/biot.201600579

Abstract: Escherichia coli, Saccharomyces cerevisiae, and Pichia pastoris are the standard platforms for biopharmaceutical production with 40% of all between 2010 to 2014 approved protein drugs produced in those microbial hosts. Typically, products overexpressed E. coli… read more here.

Keywords: process development; cell disruption; disruption; microscale ... See more keywords
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Shear to longitudinal mode conversion via second harmonic generation in a two-dimensional microscale granular crystal

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Published in 2017 at "Wave Motion"

DOI: 10.1016/j.wavemoti.2016.08.009

Abstract: Abstract Shear to longitudinal mode conversion via second harmonic generation is studied theoretically and computationally for plane waves in a two-dimensional, adhesive, hexagonally close-packed microscale granular medium. The model includes translational and rotational degrees of… read more here.

Keywords: shear longitudinal; mode; mode conversion; longitudinal mode ... See more keywords
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Engineering of a Microscale Niche for Pancreatic Tumor Cells Using Bioactive Film Coatings Combined with 3D-Architectured Scaffolds.

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Published in 2022 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.2c01747

Abstract: Two-photon polymerization has recently emerged as a promising technique to fabricate scaffolds for three-dimensional (3D) cell culture and tissue engineering. Here, we combined 3D-printed microscale scaffolds fabricated using two-photon polymerization with a bioactive layer-by-layer film… read more here.

Keywords: cell; microscale; cell adhesion; bioactive film ... See more keywords
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Dynamic air/liquid pockets for guiding microscale flow

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Published in 2018 at "Nature Communications"

DOI: 10.1038/s41467-018-03194-z

Abstract: Microscale flows of fluids are mainly guided either by solid matrices or by liquid–liquid interfaces. However, the solid matrices are plagued with persistent fouling problems, while liquid–liquid interfaces are limited to low-pressure applications. Here we… read more here.

Keywords: liquid; liquid pockets; air liquid; flow ... See more keywords
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Enhanced Attachment and Collagen Type I Deposition of MC3T3-E1 Cells via Electrohydrodynamic Printed Sub-Microscale Fibrous Architectures

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Published in 2022 at "International Journal of Bioprinting"

DOI: 10.18063/ijb.v8i2.514

Abstract: Micro/sub-microscale fibrillar architectures of extracellular matrix play important roles in regulating cellular behaviors such as attachment, migration, and differentiation. However, the interactions between cells and organized micro/sub-microscale fibers have not been fully clarified yet. Here,… read more here.

Keywords: collagen type; sub microscale; microscale; printed sub ... See more keywords
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Training Computers to See the Built Environment Related to Physical Activity: Detection of Microscale Walkability Features Using Computer Vision

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Published in 2022 at "International Journal of Environmental Research and Public Health"

DOI: 10.3390/ijerph19084548

Abstract: The study purpose was to train and validate a deep learning approach to detect microscale streetscape features related to pedestrian physical activity. This work innovates by combining computer vision techniques with Google Street View (GSV)… read more here.

Keywords: microscale; physical activity; walkability; computer vision ... See more keywords
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Well-Defined Polyethylene Glycol Microscale Hydrogel Blocks Containing Gold Nanorods for Dual Photothermal and Chemotherapeutic Therapy

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Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14030551

Abstract: Local drug delivery offers a means of achieving a high concentration of therapeutic agents directly at the tumor site, whilst minimizing systemic toxicity. For heterogenous cancers such as glioblastoma, multimodal therapeutic approaches hold promise for… read more here.

Keywords: well defined; microscale hydrogels; gold nanorods; therapy ... See more keywords