Scaffold Hopping from Amodiaquine to Novel Nurr1 Agonist Chemotypes via Microscale Analogue Libraries
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DOI: 10.1002/cmdc.202200026
Abstract: Several lines of evidence suggest the ligand‐sensing transcription factor Nurr1 as a promising target to treat neurodegenerative diseases. Nurr1 modulators to validate and exploit this therapeutic potential are rare, however. To identify novel Nurr1 agonist… read more here.
Keywords: agonist chemotypes; nurr1 agonist; novel nurr1; microscale analogue ... See more keywords