Multiscale ATUM-FIB Microscopy Enables Targeted Ultrastructural Analysis at Isotropic Resolution
Sign Up to like & getrecommendations! Published in 2020 at "Microscopy and Microanalysis"
DOI: 10.1017/s1431927620015238
Abstract: Volume Electron Microscopy (EM) not only enables dense reconstructions of neuronal circuits but provides the tissue context for targeted high resolution visualization of selected biological structures. Currently, 3D ultrastructure can be solved by destructive techniques… read more here.
Keywords: resolution; microscopy enables; microscopy; atum ... See more keywords
EMBER multidimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2300769120
Abstract: Significance In neurodegenerative diseases, proteins fold into amyloid structures with distinct conformations (strains). There is a need to rapidly identify these amyloid conformations in situ. Here, we use machine learning on the full information available… read more here.
Keywords: spectral microscopy; multidimensional spectral; disease; microscopy ... See more keywords