Species Differences in Microsomal Metabolism of Xanthine-Derived A1 Adenosine Receptor Ligands
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DOI: 10.3390/ph14030277
Abstract: Tracer development for positron emission tomography (PET) requires thorough evaluation of pharmacokinetics, metabolism, and dosimetry of candidate radioligands in preclinical animal studies. Since variations in pharmacokinetics and metabolism of a compound occur in different species,… read more here.
Keywords: microsomal metabolism; species differences; metabolism; xanthine derived ... See more keywords