Investigating the association between human brainstem microstructural integrity and hypertension using magnetic resonance relaxometry
Sign Up to like & getrecommendations! Published in 2025 at "Hypertension Research"
DOI: 10.1038/s41440-025-02114-1
Abstract: The brainstem plays a vital role in regulating blood pressure, and disruptions to its neural pathways have been linked to hypertension. However, it remains unclear whether subtle microstructural changes in the brainstem are associated with… read more here.
Keywords: microstructural integrity; relaxometry; brainstem; myelin ... See more keywords
Central autonomic nervous tract integrity of the brain is linked to blood pressure.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of hypertension"
DOI: 10.1097/hjh.0000000000004182
Abstract: BACKGROUND Hypertension is closely associated with autonomic dysfunction. The role of the structural integrity of the central autonomic network (CAN) of the brain is insufficiently explored. Large-scale imaging data were used to investigate the relationship… read more here.
Keywords: microstructural integrity; brain; integrity; hypertension ... See more keywords
Associations of Life's Simple 7 with cerebral white matter hyperintensities and microstructural integrity: UK Biobank cohort study
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Neurology"
DOI: 10.1111/ene.15750
Abstract: The American Heart Association Life's Simple 7 (LS7) metric was used to define optimal cardiovascular and brain health, but the associations with macrostructural hyperintensities and microstructural white matter damage are unclear. The objective was to… read more here.
Keywords: hyperintensities microstructural; life simple; microstructural integrity; white matter ... See more keywords
An Investigation of Corticospinal Tract Microstructural Integrity in ARSACS Using a Profilometry MRI Analysis: Results From the PROSPAX Study
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Neurology"
DOI: 10.1111/ene.70128
Abstract: Spasticity represents a core clinical feature of Autosomal Recessive Spastic Ataxia of Charlevoix‐Saguenay (ARSACS) patients. Nonetheless, its pathophysiological substrate is poorly investigated. We assessed the microstructural integrity of the corticospinal tract (CST) using diffusion MRI… read more here.
Keywords: microstructural integrity; mri; arsacs; corticospinal tract ... See more keywords
Microstructural integrity of corticospinal and medial lemniscus tracts: Insights from diffusion tensor tractography of right-hand amputees.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of neurophysiology"
DOI: 10.1152/jn.00316.2018
Abstract: Reductions in sensory and motor activity following unilateral upper limb amputation during adulthood are associated with widespread, activity-dependent reorganization of the gray matter and white matter through the central nervous system. Likewise, in cases of… read more here.
Keywords: microstructural integrity; hand; integrity; diffusion tensor ... See more keywords
Progression of White Matter Hyperintensities Preceded by Heterogeneous Decline of Microstructural Integrity
Sign Up to like & getrecommendations! Published in 2018 at "Stroke"
DOI: 10.1161/strokeaha.118.020980
Abstract: Background and Purpose— White matter hyperintensities (WMH) are frequently seen on neuroimaging of elderly and are associated with cognitive decline and the development of dementia. Yet, the temporal dynamics of conversion of normal-appearing white matter… read more here.
Keywords: wmh; microstructural integrity; time; white matter ... See more keywords
Microstructural integrity of white matter tracts amongst older fallers: A DTI study
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0179895
Abstract: Objectives This study assesses the whole brain microstructural integrity of white matter tracts (WMT) among older individuals with a history of falls compared to non-fallers. Methods 85 participants (43 fallers, 42 non-fallers) were evaluated with… read more here.
Keywords: microstructural integrity; matter tracts; matter; non fallers ... See more keywords
Microstructural Integrity of Salvaged Penumbra after Mechanical Thrombectomy
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Neuroradiology"
DOI: 10.3174/ajnr.a6364
Abstract: BACKGROUND AND PURPOSE: There are sparse data on the microstructural integrity of salvaged penumbral tissue after mechanical thrombectomy of large-vessel occlusions. The aim of the study was to analyze possible microstructural alteration in the penumbra… read more here.
Keywords: mean diffusivity; diffusivity index; mechanical thrombectomy; integrity ... See more keywords
Gait Asymmetry in People With Parkinson’s Disease Is Linked to Reduced Integrity of Callosal Sensorimotor Regions
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2018.00215
Abstract: Background Individuals with Parkinson’s disease (PD) often manifest significant temporal and spatial asymmetries of the lower extremities during gait, which significantly contribute to mobility impairments. While the neural mechanisms underlying mobility asymmetries within this population… read more here.
Keywords: microstructural integrity; gait asymmetry; integrity; sensorimotor ... See more keywords